prikaz prve stranice dokumenta New insights into erythropoietin and erythropoietin receptor in laryngeal cancer tissue
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New insights into erythropoietin and erythropoietin receptor in laryngeal cancer tissue
Medicine, 100 (2021), 3; e23943. https://doi.org/10.1097/MD.0000000000023943
Vukelić, Jelena; Dobrila-Dintinjana, Renata; Marijić, Blažen; Maržić, Diana; Braut, Tamara; Velepič, Marko

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

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Vukelić, J., Dobrila Dintinjana, R., Marijić, B., Maržić, D., Braut, T. i Velepič, M. (2021). New insights into erythropoietin and erythropoietin receptor in laryngeal cancer tissue. Medicine, 100. (3). doi: 10.1097/MD.0000000000023943

Vukelić, Jelena, et al. "New insights into erythropoietin and erythropoietin receptor in laryngeal cancer tissue." Medicine, vol. 100, br. 3, 2021. https://doi.org/10.1097/MD.0000000000023943

Vukelić, Jelena, Renata Dobrila Dintinjana, Blažen Marijić, Diana Maržić, Tamara Braut i Marko Velepič. "New insights into erythropoietin and erythropoietin receptor in laryngeal cancer tissue." Medicine 100, br. 3 (2021). https://doi.org/10.1097/MD.0000000000023943

Vukelić, J., et al. (2021) 'New insights into erythropoietin and erythropoietin receptor in laryngeal cancer tissue', Medicine, 100(3). doi: 10.1097/MD.0000000000023943

Vukelić J, Dobrila Dintinjana R, Marijić B, Maržić D, Braut T, Velepič M. New insights into erythropoietin and erythropoietin receptor in laryngeal cancer tissue. Medicine [Internet]. 22.01.2021. [pristupljeno 02.05.2024.];100(3). doi: 10.1097/MD.0000000000023943

J. Vukelić, R. Dobrila Dintinjana, B. Marijić, D. Maržić, T. Braut i M. Velepič, "New insights into erythropoietin and erythropoietin receptor in laryngeal cancer tissue", Medicine, vol. 100, br. 3, Siječanj 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:613805. [Citirano: 02.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:613805
Podaci o radu
Naslov (engleski)New insights into erythropoietin and erythropoietin receptor in laryngeal cancer tissue
AutorJelena Vukelić
AutorRenata Dobrila-Dintinjana
AutorBlažen Marijić
AutorDiana Maržić
AutorTamara Braut
AutorMarko Velepič
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za onkologiju i radioterapiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za otorinolaringologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Otorinolaringologija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Onkologija
Sažetak (engleski)
To investigate whether laryngeal cancer cells express erythropoietin (Epo) and erythropoietin receptor (EpoR) and what is their possible relationship with clinical and pathological features of the tumor. We performed immunohistochemical analysis of Epo and EpoR expression on 78 tissue samples of invasive and in situ squamous cell laryngeal carcinoma. The statistical analysis showed a weak positive and statistically significant correlation of EpoHS and EpoR HS expression levels. Epo HS and EpoR HS levels did not correlate with patient sex or age, type of diagnosis, cancer stage, histological tumor grade, presence or absence of disease recurrence, type of oncologic cancer therapy provided, or results of selected laboratory blood work. The results show a statistically significant difference in Epo expression with respect to survival. We confirmed the presence of Epo an EpoR in malignant laryngeal tumors and demonstrated the correlation between Epo expression and survival. Further studies are needed to more precisely define the role of Epo and EpoR in treatment of patients with laryngeal cancer.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaMedicine
Brojčani podacivol. 100, br. 3, e23943
p-ISSN0025-7974
e-ISSN1536-5964
DOIhttps://doi.org/10.1097/MD.0000000000023943
URN:NBNurn:nbn:hr:184:613805
Datum objave publikacije2021-01-22
URL dokumentahttps://journals.lww.com/10.1097/MD.0000000000023943
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno 4.0 međunarodna (CC BY-NC 4.0)
Datum i vrijeme pohrane2021-02-18 21:00:27