Oral cavity squamous cell carcinoma is a tumour of epithelial descent . It appears most often with people who drinks alcohol and smoke cigarettes. The cancer can appear anywhere in the mouth, but the most common locations are bottom of the mouth and tongue, ie. it' s ventral surface. Primary metastasizes to regional lymphatic nodes door. The selection and treatment methods depends on the existence of regional metastasis, sublocalization of primary tumor and the size of tumor. Precancerous lesions and conditions are morphological changed tissues that have a higher incidence to increase into tumor then normal equivalent. The most dangerous precancerous lesion is erythroplakia. The clinical features of early cancer of the oral cavity is in the form of erythroplakia. The later stage of cancer has the appearance of ulcers, and it's then easier to spot. The most important in the treatment of cancer is early diagnosis . It's very important to educate all health professionals with signs and appearance of oral cancer in the early stages and teach them how important it is for successful treatment. The most important classification of cancers of oral cavity is TNM classification. It describes the size of the tumor, the presence of regional metastases and distant metastases. Treatment of cancer of the oral cavity is originally surgery. Adjuvant therapy are radiation therapy and chemotherapy. The right treatment is very difficult to define because it's necessary to consider the general condition of the patient, the specificity of the tumor, metastasis, the ability of a team for conducting the processes, etc.