prikaz prve stranice dokumenta Epitope Recognition of a Monoclonal Antibody Raised against a Synthetic Glycerol Phosphate Based Teichoic Acid
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Epitope Recognition of a Monoclonal Antibody Raised against a Synthetic Glycerol Phosphate Based Teichoic Acid
ACS Chemical Biology, 16 (2021), 8; 1344-1349. https://doi.org/10.1021/acschembio.1c00422
Berni, Francesca; Kalfopoulou, Ermioni; Gimeno Cardells, Ana M.; Carboni, Filippo; van der Es, Daan; Romero-Saavedra, Felipe; Laverde, Diana; Miklić, Karmela; Malić, Suzana; Roviš, Tihana L.; Jonjić, Stipan; Ali, Sara; Overkleeft, Herman S.; Hokke, Cornelis H.; van Diepen, Angela; Adamo, Roberto; Jimenez-Barbero, Jesus; van der Marel, Gijsbert A.; Huebner, Johannes; Codée, Jeroen D. C. Više autora...

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

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Berni, F., Kalfopoulou, E., Gimeno Cardells, A. M., Carboni, F., van der Es, D., Romero Saavedra, F. ... Codée, J. D. C. (2021). Epitope Recognition of a Monoclonal Antibody Raised against a Synthetic Glycerol Phosphate Based Teichoic Acid. ACS Chemical Biology, 16. (8), 1344-1349. doi: 10.1021/acschembio.1c00422

Berni, Francesca, et al. "Epitope Recognition of a Monoclonal Antibody Raised against a Synthetic Glycerol Phosphate Based Teichoic Acid." ACS Chemical Biology, vol. 16, br. 8, 2021, str. 1344-1349. https://doi.org/10.1021/acschembio.1c00422

Berni, Francesca, Ermioni Kalfopoulou, Ana M. Gimeno Cardells, Filippo Carboni, Daan van der Es, Felipe Romero Saavedra, Diana Laverde, et al. "Epitope Recognition of a Monoclonal Antibody Raised against a Synthetic Glycerol Phosphate Based Teichoic Acid." ACS Chemical Biology 16, br. 8 (2021): 1344-1349. https://doi.org/10.1021/acschembio.1c00422

Berni, F., et al. (2021) 'Epitope Recognition of a Monoclonal Antibody Raised against a Synthetic Glycerol Phosphate Based Teichoic Acid', ACS Chemical Biology, 16(8), str. 1344-1349. doi: 10.1021/acschembio.1c00422

Berni F, Kalfopoulou E, Gimeno Cardells AM, Carboni F, van der Es D, Romero Saavedra F, i sur.. Epitope Recognition of a Monoclonal Antibody Raised against a Synthetic Glycerol Phosphate Based Teichoic Acid. ACS Chemical Biology [Internet]. 13.07.2021. [pristupljeno 13.05.2024.];16(8):1344-1349. doi: 10.1021/acschembio.1c00422

F. Berni, et al., "Epitope Recognition of a Monoclonal Antibody Raised against a Synthetic Glycerol Phosphate Based Teichoic Acid", ACS Chemical Biology, vol. 16, br. 8, str. 1344-1349, Srpanj 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:454657. [Citirano: 13.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:454657
Podaci o radu
Naslov (engleski)Epitope Recognition of a Monoclonal Antibody Raised against a Synthetic Glycerol Phosphate Based Teichoic Acid
AutorFrancesca Berni
AutorErmioni Kalfopoulou
AutorAna M. Gimeno Cardells
AutorFilippo Carboni
AutorDaan van der Es
AutorFelipe Romero-Saavedra
AutorDiana Laverde
AutorKarmela Miklić
AutorSuzana Malić
AutorTihana L. Roviš
AutorStipan Jonjić
AutorSara Ali
AutorHerman S. Overkleeft
AutorCornelis H. Hokke
AutorAngela van Diepen
AutorRoberto Adamo
AutorJesus Jimenez-Barbero
AutorGijsbert A. van der Marel
AutorJohannes Huebner
AutorJeroen D. C. Codée
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Centar za proteomiku)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
Glycerol phosphate (GroP)-based teichoic acids (TAs) are antigenic cell-wall components found in both enterococcus and staphylococcus species. Their immunogenicity has been explored using both native and synthetic structures, but no details have yet been reported on the structural basis of their interaction with antibodies. This work represents the first case study in which a monoclonal antibody, generated against a synthetic TA, was developed and employed for molecular-level binding analysis using TA microarrays, ELISA, SPR-analyses, and STD-NMR spectroscopy. Our findings show that the number and the chirality of the GroP residues are crucial for interaction and that the sugar appendage contributes to the presentation of the backbone to the binding site of the antibody.
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pismo
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaACS Chemical Biology
Brojčani podacivol. 16, br. 8, str. 1344-1349
p-ISSN1554-8929
e-ISSN1554-8937
DOIhttps://doi.org/10.1021/acschembio.1c00422
URN:NBNurn:nbn:hr:184:454657
Datum objave publikacije2021-07-13
ProjektŠifra: 675671
Naziv (engleski): A training network for the rational design of the next generation of well-defined glycoconjugate vaccines
Kratica: GLYCOVAX
Pravna nadležnost: eu
Financijer: EC
Linija financiranja: H2020
URL dokumentahttps://pubs.acs.org/doi/10.1021/acschembio.1c00422
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2021-12-30 13:06:00