prikaz prve stranice dokumenta Colocalization of Granulysin Protein Forms with Perforin and LAMP-1 in Decidual Lymphocytes During Early Pregnancy
Rad je dostupan svim korisnicima iz sustava znanosti i visokog obrazovanja RH
Znanstveni rad - Izvorni znanstveni rad
Colocalization of Granulysin Protein Forms with Perforin and LAMP-1 in Decidual Lymphocytes During Early Pregnancy
American Journal of Reproductive Immunology, 75 (2016), 6; 619-630. https://doi.org/10.1111/aji.12503
Dominović, Marin; Laškarin, Gordana; Glavan Gačanin, Lana; Haller, Herman; Rukavina, Daniel

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

Citirajte ovaj rad

Dominović, M., Laškarin, G., Glavan Gačanin, L., Haller, H. i Rukavina, D. (2016). Colocalization of Granulysin Protein Forms with Perforin and LAMP-1 in Decidual Lymphocytes During Early Pregnancy. American Journal of Reproductive Immunology, 75. (6), 619-630. doi: 10.1111/aji.12503

Dominović, Marin, et al. "Colocalization of Granulysin Protein Forms with Perforin and LAMP-1 in Decidual Lymphocytes During Early Pregnancy." American Journal of Reproductive Immunology, vol. 75, br. 6, 2016, str. 619-630. https://doi.org/10.1111/aji.12503

Dominović, Marin, Gordana Laškarin, Lana Glavan Gačanin, Herman Haller i Daniel Rukavina. "Colocalization of Granulysin Protein Forms with Perforin and LAMP-1 in Decidual Lymphocytes During Early Pregnancy." American Journal of Reproductive Immunology 75, br. 6 (2016): 619-630. https://doi.org/10.1111/aji.12503

Dominović, M., et al. (2016) 'Colocalization of Granulysin Protein Forms with Perforin and LAMP-1 in Decidual Lymphocytes During Early Pregnancy', American Journal of Reproductive Immunology, 75(6), str. 619-630. doi: 10.1111/aji.12503

Dominović M, Laškarin G, Glavan Gačanin L, Haller H, Rukavina D. Colocalization of Granulysin Protein Forms with Perforin and LAMP-1 in Decidual Lymphocytes During Early Pregnancy. American Journal of Reproductive Immunology [Internet]. 2016. [pristupljeno 19.04.2024.];75(6):619-630. doi: 10.1111/aji.12503

M. Dominović, G. Laškarin, L. Glavan Gačanin, H. Haller i D. Rukavina, "Colocalization of Granulysin Protein Forms with Perforin and LAMP-1 in Decidual Lymphocytes During Early Pregnancy", American Journal of Reproductive Immunology, vol. 75, br. 6, str. 619-630, 2016. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:681638. [Citirano: 19.04.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:681638
Podaci o radu
Naslov (engleski)Colocalization of Granulysin Protein Forms with Perforin and LAMP-1 in Decidual Lymphocytes During Early Pregnancy
AutorMarin Dominović
MBZ: 316571
AutorGordana Laškarin
AutorLana Glavan Gačanin
AutorHerman Haller
AutorDaniel Rukavina
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za fiziologiju, imunologiju i patofiziologiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za ginekologiju i opstetriciju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Imunologija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Fiziologija čovjeka
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
PROBLEM: Granulysin (GNLY) occurs in two forms, which have molecular weights of 9 and 15 kDa. We analyzed the cytotoxic potential of decidual lymphocytes (DLs) and peripheral blood lymphocytes (PBLs) based on the forms of GNLY that colocalizes with perforin (PER) and LAMP-1 following activation. METHODS: The forms of GNLY were detected by using confocal microscopy. We investigated the colocalization with PER and LAMP-1 in freshly isolated and activated DLs and PBLs. RESULTS: Activation of DLs and PBLs by K- 562 cells increased the colocalization of 9 kDa GNLY with PER and LAMP- 1. K-562 cells transfected with HLA-C decreased 9 kDa GNLY colocalization with PER in DLs only. IL-15 in DLs decreased 9 kDa GNLY and LAMP-1 colocalization, but increased both 15 kDa GNLY and LAMP-1, and PER and LAMP-1 colocalization. CONCLUSION: Activated DLs and PBLs show greater cytotoxic potential based on increased colocalization of 9 kDa GNLY and PER. HLA-C and IL-15 affect DLs, indicating their role in maintaining the pregnancy tolerance.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaAmerican Journal of Reproductive Immunology
Brojčani podacivol. 75, br. 6, str. 619-630
p-ISSN1046-7408
e-ISSN1600-0897
DOIhttps://doi.org/10.1111/aji.12503
URN:NBNurn:nbn:hr:184:681638
Datum objave publikacije2016
URL dokumentahttp://bib.irb.hr/817020
Vrsta resursaTekst
Prava pristupaOgraničen pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-02-11 16:32:17