prikaz prve stranice dokumenta Serum adipocytokines are associated with microalbuminuria in patients with type 1 diabetes and incipient chronic complications
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Serum adipocytokines are associated with microalbuminuria in patients with type 1 diabetes and incipient chronic complications
Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 13 (2019); 496-499. https://doi.org/10.1016/j.dsx.2018.11.001
Bulum, Tomislav; Vučić Lovrenčić, Marijana; Tomić, Martina; Vučković Rebrina, Sandra; Roso, Vinko; Kolarić, Branko; Vuksan, Vladimir; Duvnjak, Lea

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

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Bulum, T., Vučić Lovrenčić, M., Tomić, M., Vučković Rebrina, S., Roso, V., Kolarić, B. ... Duvnjak, L. (2019). Serum adipocytokines are associated with microalbuminuria in patients with type 1 diabetes and incipient chronic complications. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 13., 496-499. doi: 10.1016/j.dsx.2018.11.001

Bulum, Tomislav, et al. "Serum adipocytokines are associated with microalbuminuria in patients with type 1 diabetes and incipient chronic complications." Diabetes & Metabolic Syndrome: Clinical Research & Reviews, vol. 13, 2019, str. 496-499. https://doi.org/10.1016/j.dsx.2018.11.001

Bulum, Tomislav, Marijana Vučić Lovrenčić, Martina Tomić, Sandra Vučković Rebrina, Vinko Roso, Branko Kolarić, Vladimir Vuksan i Lea Duvnjak. "Serum adipocytokines are associated with microalbuminuria in patients with type 1 diabetes and incipient chronic complications." Diabetes & Metabolic Syndrome: Clinical Research & Reviews 13 (2019): 496-499. https://doi.org/10.1016/j.dsx.2018.11.001

Bulum, T., et al. (2019) 'Serum adipocytokines are associated with microalbuminuria in patients with type 1 diabetes and incipient chronic complications', Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 13, str. 496-499. doi: 10.1016/j.dsx.2018.11.001

Bulum T, Vučić Lovrenčić M, Tomić M, Vučković Rebrina S, Roso V, Kolarić B, i sur.. Serum adipocytokines are associated with microalbuminuria in patients with type 1 diabetes and incipient chronic complications. Diabetes & Metabolic Syndrome: Clinical Research & Reviews [Internet]. 2019. [pristupljeno 09.05.2024.];13:496-499. doi: 10.1016/j.dsx.2018.11.001

T. Bulum, et al., "Serum adipocytokines are associated with microalbuminuria in patients with type 1 diabetes and incipient chronic complications", Diabetes & Metabolic Syndrome: Clinical Research & Reviews, vol. 13, str. 496-499, 2019. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:672554. [Citirano: 09.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:672554
Podaci o radu
Naslov (engleski)Serum adipocytokines are associated with microalbuminuria in patients with type 1 diabetes and incipient chronic complications
AutorTomislav Bulum
MBZ: 332203
AutorMarijana Vučić Lovrenčić
MBZ: 176744
AutorMartina Tomić
MBZ: 272561
AutorSandra Vučković Rebrina
MBZ: 177894
AutorVinko Roso
AutorBranko Kolarić
AutorVladimir Vuksan
MBZ: 53962
AutorLea Duvnjak
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za socijalnu medicinu i epidemiologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Recent studies have implicated possible contribution of adipocytokines in development and progression of microvascular complications in patients with type 1 diabetes (T1DM). The aim of our study was to investigate relationship between adipocytokines, namely leptin, resistin, adiponectin and dipeptidyl peptidase-4 (DPP-4) activity, with albuminuria in T1DM. This study included 202 T1DM without or with incipient microvascular complications. Urinary albumin excretion rate (UAE) was measured from at least two 24-h urine samples. Serum DPP-4 activity was measured by a colorimetric assay procured, and the level of adiponectin, leptin, and resistin was determined by the ELISA method. Serum DPP-4 activity and adiponectin was significantly higher in patients with normoalbuminuria compared to patients with microalbuminuria (47 vs 36 U/L, and 10.9 vs 7.3 ug/mL, respectively, p≤0.02). In multivariate logistic regression analysis adiponectin and serum DPP-4 activity was significantly associated with risk of microalbuminuria in our subjects (p≤0.04), with odds ratios of 0.72 to 0.99. However, after adjustment for age, sex, HbA1c, duration of diabetes and BMI, only serum DPP-4 activity was significantly associated with risk of microalbuminuria (p=0.008). The results of our study suggest that serum DPP-4 activity is lower in T1DM with microalbuminuria. Prospective studies are warranted to evaluate the relationship between serum DPP-4 activity and progression and development of albuminuria and nephropathy in T1DM.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaDiabetes & Metabolic Syndrome: Clinical Research & Reviews
Brojčani podacivol. 13, str. 496-499
p-ISSN1871-4021
DOIhttps://doi.org/10.1016/j.dsx.2018.11.001
URN:NBNurn:nbn:hr:184:672554
Datum objave publikacije2019
URL dokumentahttp://bib.irb.hr/965217
Vrsta resursaTekst
Prava pristupaInstitucijski pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-03-08 14:38:47