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The effect of nickel ions on the susceptibility of bacteria to ciprofloxacin and ampicillin
Folia Microbiologica, (2022); https://doi.org/10.1007/s12223-022-00960-x
Pavlić, Andrej; Gobin, Ivana; Begić, Gabrijela; Tota, Marin; Abram, Maja; Špalj, Stjepan

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

Citirajte ovaj rad

Pavlić, A., Gobin, I., Begić, G., Tota, M., Abram, M. i Špalj, S.. The effect of nickel ions on the susceptibility of bacteria to ciprofloxacin and ampicillin. Folia Microbiologica. doi: 10.1007/s12223-022-00960-x

Pavlić, Andrej, et al. "The effect of nickel ions on the susceptibility of bacteria to ciprofloxacin and ampicillin." Folia Microbiologica. https://doi.org/10.1007/s12223-022-00960-x

Pavlić, Andrej, Ivana Gobin, Gabrijela Begić, Marin Tota, Maja Abram i Stjepan Špalj. "The effect of nickel ions on the susceptibility of bacteria to ciprofloxacin and ampicillin." Folia Microbiologica. https://doi.org/10.1007/s12223-022-00960-x

Pavlić, A., et al. 'The effect of nickel ions on the susceptibility of bacteria to ciprofloxacin and ampicillin', Folia Microbiologica. doi: 10.1007/s12223-022-00960-x

Pavlić A, Gobin I, Begić G, Tota M, Abram M, Špalj S. The effect of nickel ions on the susceptibility of bacteria to ciprofloxacin and ampicillin. Folia Microbiologica [Internet]. [pristupljeno 25.12.2024.]. doi: 10.1007/s12223-022-00960-x

A. Pavlić, I. Gobin, G. Begić, M. Tota, M. Abram i S. Špalj, "The effect of nickel ions on the susceptibility of bacteria to ciprofloxacin and ampicillin", Folia Microbiologica. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:635835. [Citirano: 25.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:635835
Podaci o radu
Naslov (engleski)The effect of nickel ions on the susceptibility of bacteria to ciprofloxacin and ampicillin
AutorAndrej Pavlić
AutorIvana Gobin
AutorGabrijela Begić
AutorMarin Tota
AutorMaja Abram
AutorStjepan Špalj
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za medicinsku kemiju, biokemiju i kliničku kemiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Dentalna medicina
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Medicinska mikrobiologija
Sažetak (engleski)
Abstract To explore the interaction efects of ciprofoxacin and ampicillin with nickel on the growth of bacteria, Staphylococcus aureus strain ATCC 29213, Enterococcus faecalis ATCC 29212 and Escherichia coli ATCC 25922 were used. Minimum inhibitory concentrations (MICs) were determined for nickel, ciprofoxacin and ampicillin, and the checkerboard method was used to assess their cumulative efects on bacterial growth. The interactions between the metal and antibiotics were assessed by the fractional inhibitory concentration (FIC). The MICs for ciprofoxacin and ampicillin were 0.31 and 1 mg/L for E. faecalis, 0.62 and 1 mg/L for S. aureus and 0.005 and 2.5 for E. coli, respectively. The MIC for nickel was 1000 mg/L for all bacteria. The FIC results for ciprofoxacin and nickel demonstrated an antagonistic efect of the two agents on the growth of E. coli and E. faecalis and an additive efect on S. aureus. The FICs for ampicillin and nickel demonstrated a synergistic efect on the growth of E. faecalis and E. coli. Diferent interactions of metals and antibiotics were observed depending on the bacteria and the type of antibiotic.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objavePrihvaćen za objavljivanje
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaFolia Microbiologica
p-ISSN0015-5632
e-ISSN1874-9356
DOIhttps://doi.org/10.1007/s12223-022-00960-x
URN:NBNurn:nbn:hr:184:635835
Datum prihvaćanja za tisak2022-02-19
URL dokumentahttps://link.springer.com/10.1007/s12223-022-00960-x
Vrsta resursaTekst
Prava pristupaOgraničen pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-04-05 15:12:54