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The Influence of Hyaluronic Acid Adjunctive Therapy of Periodontitis on Salivary Markers of Oxidative Stress: Randomized, Controlled Clinical Trial
Antioxidants, 11 (2022), 1; 135. https://doi.org/10.3390/antiox11010135
Olszewska-Czyz, Iwona; Kralik, Kristina; Tota, Marin; Prpić, Jelena

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

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Olszewska Czyz, I., Kralik, K., Tota, M. i Prpić, J. (2022). The Influence of Hyaluronic Acid Adjunctive Therapy of Periodontitis on Salivary Markers of Oxidative Stress: Randomized, Controlled Clinical Trial. Antioxidants, 11. (1). doi: 10.3390/antiox11010135

Olszewska Czyz, Iwona, et al. "The Influence of Hyaluronic Acid Adjunctive Therapy of Periodontitis on Salivary Markers of Oxidative Stress: Randomized, Controlled Clinical Trial." Antioxidants, vol. 11, br. 1, 2022. https://doi.org/10.3390/antiox11010135

Olszewska Czyz, Iwona, Kristina Kralik, Marin Tota i Jelena Prpić. "The Influence of Hyaluronic Acid Adjunctive Therapy of Periodontitis on Salivary Markers of Oxidative Stress: Randomized, Controlled Clinical Trial." Antioxidants 11, br. 1 (2022). https://doi.org/10.3390/antiox11010135

Olszewska Czyz, I., et al. (2022) 'The Influence of Hyaluronic Acid Adjunctive Therapy of Periodontitis on Salivary Markers of Oxidative Stress: Randomized, Controlled Clinical Trial', Antioxidants, 11(1). doi: 10.3390/antiox11010135

Olszewska Czyz I, Kralik K, Tota M, Prpić J. The Influence of Hyaluronic Acid Adjunctive Therapy of Periodontitis on Salivary Markers of Oxidative Stress: Randomized, Controlled Clinical Trial. Antioxidants [Internet]. 07.01.2022. [pristupljeno 26.04.2024.];11(1). doi: 10.3390/antiox11010135

I. Olszewska Czyz, K. Kralik, M. Tota i J. Prpić, "The Influence of Hyaluronic Acid Adjunctive Therapy of Periodontitis on Salivary Markers of Oxidative Stress: Randomized, Controlled Clinical Trial", Antioxidants, vol. 11, br. 1, Siječanj 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:026363. [Citirano: 26.04.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:026363
Podaci o radu
Naslov (engleski)The Influence of Hyaluronic Acid Adjunctive Therapy of Periodontitis on Salivary Markers of Oxidative Stress: Randomized, Controlled Clinical Trial
AutorIwona Olszewska-Czyz
AutorKristina Kralik
AutorMarin Tota
AutorJelena Prpić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za oralnu medicinu i parodontologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Dentalna medicina
Sažetak (engleski)
Periodontitis is a common oral disease affecting the tooth-supporting tissues. Bacteria have been long viewed as the main causative factor in its development; however, many investigations have proved that aberrant immune and inflammatory response and the resulting misbalance between the damage caused by reactive oxygen species and the antioxidant capacity of tissues may be an underlying factor in disease progression that reduces healing potential. The objective of the current trial is to assess the outcomes of the addition of hyaluronic acid (HA) to standard non-surgical periodontal therapy (NST) on some major oxidative stress markers in saliva. HA-based gel designed for dental application was used and the measurements were taken after 3 months. HA adjunctive therapy had a significantly greater increase in markers with antioxidant properties as well as total antioxidant capacity compared to standard NST alone. Furthermore, clinically measured levels of gingival inflammation (bleeding on probing-BOP) and periodontal destruction (clinical attachment loss-CAL) were significantly correlated with these markers, and the correlation was negative. This investigation demonstrates that HA may indeed express antioxidant properties and improve the antioxidant capacity of periodontal tissues, thus improving the prognosis for the teeth and the results of periodontal therapy. Further investigations will be necessary to determine the duration of these effects over time.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaAntioxidants
Brojčani podacivol. 11, br. 1, 135
e-ISSN2076-3921
DOIhttps://doi.org/10.3390/antiox11010135
URN:NBNurn:nbn:hr:184:026363
Datum objave publikacije2022-01-07
URL dokumentahttps://www.mdpi.com/2076-3921/11/1/135
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2022-04-22 11:46:29