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A Comparison of Bone Marrow Morphology and Peripheral Blood Findings in Low and High Level JAK2 V617F Allele Burden
Diagnostics, 13 (2023), 12; 2086. https://doi.org/10.3390/diagnostics13122086
Babarović, Emina; Marijić, Blažen; Vranić, Luka; Ban, Josipa; Valković, Toni; Hadžisejdić, Ita

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

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Babarović, E., Marijić, B., Vranić, L., Ban, J., Valković, T. i Hadžisejdić, I. (2023). A Comparison of Bone Marrow Morphology and Peripheral Blood Findings in Low and High Level JAK2 V617F Allele Burden. Diagnostics, 13. (12). doi: 10.3390/diagnostics13122086

Babarović, Emina, et al. "A Comparison of Bone Marrow Morphology and Peripheral Blood Findings in Low and High Level JAK2 V617F Allele Burden." Diagnostics, vol. 13, br. 12, 2023. https://doi.org/10.3390/diagnostics13122086

Babarović, Emina, Blažen Marijić, Luka Vranić, Josipa Ban, Toni Valković i Ita Hadžisejdić. "A Comparison of Bone Marrow Morphology and Peripheral Blood Findings in Low and High Level JAK2 V617F Allele Burden." Diagnostics 13, br. 12 (2023). https://doi.org/10.3390/diagnostics13122086

Babarović, E., et al. (2023) 'A Comparison of Bone Marrow Morphology and Peripheral Blood Findings in Low and High Level JAK2 V617F Allele Burden', Diagnostics, 13(12). doi: 10.3390/diagnostics13122086

Babarović E, Marijić B, Vranić L, Ban J, Valković T, Hadžisejdić I. A Comparison of Bone Marrow Morphology and Peripheral Blood Findings in Low and High Level JAK2 V617F Allele Burden. Diagnostics [Internet]. 16.06.2023. [pristupljeno 24.12.2024.];13(12). doi: 10.3390/diagnostics13122086

E. Babarović, B. Marijić, L. Vranić, J. Ban, T. Valković i I. Hadžisejdić, "A Comparison of Bone Marrow Morphology and Peripheral Blood Findings in Low and High Level JAK2 V617F Allele Burden", Diagnostics, vol. 13, br. 12, Lipanj 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:539187. [Citirano: 24.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:539187
Podaci o radu
Naslov (engleski)A Comparison of Bone Marrow Morphology and Peripheral Blood Findings in Low and High Level JAK2 V617F Allele Burden
AutorEmina Babarović
AutorBlažen Marijić
AutorLuka Vranić
AutorJosipa Ban
AutorToni Valković
AutorIta Hadžisejdić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za opću patologiju i patološku anatomiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za otorinolaringologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Cases with low level JAK2 V617F mutations are increasingly detected; however, the clinical interpretation of the low allele JAK2 burden may be challenging. The aim of this study is to analyze and compare the bone marrow morphology and peripheral blood findings in the low level JAK2 V617F allele burden (≤15% of JAK2) and high JAK2 V617F mutation burden patients (>15% JAK2). In total, 122 JAK2 V617F positive cases with concomitant bone marrow biopsies and peripheral blood findings were re-evaluated (62 low and 60 high level JAK2 V617F positive). Within the low burden group, normal looking megakaryocytes (p = 0.0005) were more frequently found, compared with those with no atypia (p = 0.0003), their number was more frequently not increased (p = 0.009), and they did not form clusters (p = 0.001). We found statistically significant difference in the number of platelet (p = 0.0003) and hematocrit levels (p = 0.032) when comparing the JAK2 V617F
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaDiagnostics
Brojčani podacivol. 13, br. 12, 2086
e-ISSN2075-4418
DOIhttps://doi.org/10.3390/diagnostics13122086
URN:NBNurn:nbn:hr:184:539187
Datum objave publikacije2023-06-16
URL dokumentahttps://www.mdpi.com/2075-4418/13/12/2086
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2023-06-19 10:38:18