prikaz prve stranice dokumenta Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells
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Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells
American Journal of Reproductive Immunology, 59 (2008), 5; 433-445. https://doi.org/10.1111/j.1600-0897.2008.00599.x
Laškarin, Gordana; Redžović, Arnela; Rubeša, Željka; Mantovani, Alberto; Allavena, Paola; Haller, Herman; Vlastelić, Ivan; Rukavina, Daniel

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

Citirajte ovaj rad

Laškarin, G., Redžović, A., Rubeša, Ž., Mantovani, A., Allavena, P., Haller, H. ... Rukavina, D. (2008). Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells. American Journal of Reproductive Immunology, 59. (5), 433-445. doi: 10.1111/j.1600-0897.2008.00599.x

Laškarin, Gordana, et al. "Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells." American Journal of Reproductive Immunology, vol. 59, br. 5, 2008, str. 433-445. https://doi.org/10.1111/j.1600-0897.2008.00599.x

Laškarin, Gordana, Arnela Redžović, Željka Rubeša, Alberto Mantovani, Paola Allavena, Herman Haller, Ivan Vlastelić i Daniel Rukavina. "Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells." American Journal of Reproductive Immunology 59, br. 5 (2008): 433-445. https://doi.org/10.1111/j.1600-0897.2008.00599.x

Laškarin, G., et al. (2008) 'Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells', American Journal of Reproductive Immunology, 59(5), str. 433-445. doi: 10.1111/j.1600-0897.2008.00599.x

Laškarin G, Redžović A, Rubeša Ž, Mantovani A, Allavena P, Haller H, i sur.. Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells. American Journal of Reproductive Immunology [Internet]. 09.04.2008. [pristupljeno 29.12.2024.];59(5):433-445. doi: 10.1111/j.1600-0897.2008.00599.x

G. Laškarin, et al., "Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells", American Journal of Reproductive Immunology, vol. 59, br. 5, str. 433-445, Travanj 2008. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:737446. [Citirano: 29.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:737446
Podaci o radu
Naslov (engleski)Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells
AutorGordana Laškarin
AutorArnela Redžović
AutorŽeljka Rubeša
AutorAlberto Mantovani
AutorPaola Allavena
AutorHerman Haller
AutorIvan Vlastelić
AutorDaniel Rukavina
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za fiziologiju, imunologiju i patofiziologiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za ginekologiju i opstetriciju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Imunologija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Ginekologija i opstetricija
Sažetak (engleski)
ProblemDendritic cells (DC)⁄natural killer (NK) cells interactions in the deciduasof early human pregnancies were analyzedin vitro.Method of studyPhenotype, cytokine expression and⁄or cytolytic mediators’ expressionwere measured by flow cytometry in NK and DC from the freshly iso-lated decidual mononuclear cells or after their purification and co-cul-turein vitro.Proliferationof5(6)-CarboxyfluoresceindiacetateN-succinimidyl ester (CFSE)-labeled CD56+cells was analyzed by flowcytometry after the co-culture with CD1a+or CD83+DC.ResultsDecidual CD1a+cells show less mature phenotype with no expression ofCD197, lower expression of CD80 and CD86 and higher expression ofCD206 and CD195 in comparison to CD83+cells. Interleukin (IL)-15,interferon-cand tumor necrosis factor-aproductions were higher inimmature than mature DC, whereas IL-10 and IL-18 were equally pro-duced in both subpopulations. Immature DC increase perforin, FasL andTRAIL protein expression and proliferation of NK cells, but decreasetheir intracellular IL-15 production. Mature DC caused less efficient pro-liferation of NK cells, and did not affect cytokine and cytolytic mediatorexpression.ConclusionThese results suggest that decidual CD1a+cells regulate and shape NKcell function more profoundly than CD83+cells in decidua.ORIGINAL ARTICLEAmerican Journal of Reproductive Immunology59(2008) 433–445ª2008 The AuthorsJournal compilationª2008 Blackwell Munksgaard433
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
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Naslov časopisaAmerican Journal of Reproductive Immunology
Brojčani podacivol. 59, br. 5, str. 433-445
p-ISSN1046-7408
DOIhttps://doi.org/10.1111/j.1600-0897.2008.00599.x
URN:NBNurn:nbn:hr:184:737446
Datum objave publikacije2008-04-09
URL dokumentahttps://onlinelibrary.wiley.com/doi/10.1111/j.1600-0897.2008.00599.x
Vrsta resursaTekst
Prava pristupaOgraničen pristup
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Datum i vrijeme pohrane2023-06-30 09:04:27