prikaz prve stranice dokumenta Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells
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Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells
American Journal of Reproductive Immunology, 59 (2008), 5; 433-445. https://doi.org/10.1111/j.1600-0897.2008.00599.x
Laškarin, Gordana; Redžović, Arnela; Rubeša, Željka; Mantovani, Alberto; Allavena, Paola; Haller, Herman; Vlastelić, Ivan; Rukavina, Daniel

Institucijski repozitorij: Repozitorij Medicinskog fakulteta u Rijeci

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Laškarin, G., Redžović, A., Rubeša, Ž., Mantovani, A., Allavena, P., Haller, H. ... Rukavina, D. (2008). Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells. American Journal of Reproductive Immunology, 59. (5), 433-445. doi: 10.1111/j.1600-0897.2008.00599.x

Laškarin, Gordana, et al. "Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells." American Journal of Reproductive Immunology, vol. 59, br. 5, 2008, str. 433-445. https://doi.org/10.1111/j.1600-0897.2008.00599.x

Laškarin, Gordana, Arnela Redžović, Željka Rubeša, Alberto Mantovani, Paola Allavena, Herman Haller, Ivan Vlastelić i Daniel Rukavina. "Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells." American Journal of Reproductive Immunology 59, br. 5 (2008): 433-445. https://doi.org/10.1111/j.1600-0897.2008.00599.x

Laškarin, G., et al. (2008) 'Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells', American Journal of Reproductive Immunology, 59(5), str. 433-445. doi: 10.1111/j.1600-0897.2008.00599.x

Laškarin G, Redžović A, Rubeša Ž, Mantovani A, Allavena P, Haller H, i sur.. Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells. American Journal of Reproductive Immunology [Internet]. 09.04.2008. [pristupljeno 07.11.2024.];59(5):433-445. doi: 10.1111/j.1600-0897.2008.00599.x

G. Laškarin, et al., "Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells", American Journal of Reproductive Immunology, vol. 59, br. 5, str. 433-445, Travanj 2008. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:737446. [Citirano: 07.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:737446
Podaci o radu
Naslov (engleski)Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells
AutorGordana Laškarin
AutorArnela Redžović
AutorŽeljka Rubeša
AutorAlberto Mantovani
AutorPaola Allavena
AutorHerman Haller
AutorIvan Vlastelić
AutorDaniel Rukavina
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za fiziologiju, imunologiju i patofiziologiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za ginekologiju i opstetriciju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Imunologija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Ginekologija i opstetricija
Sažetak (engleski)
ProblemDendritic cells (DC)⁄natural killer (NK) cells interactions in the deciduasof early human pregnancies were analyzedin vitro.Method of studyPhenotype, cytokine expression and⁄or cytolytic mediators’ expressionwere measured by flow cytometry in NK and DC from the freshly iso-lated decidual mononuclear cells or after their purification and co-cul-turein vitro.Proliferationof5(6)-CarboxyfluoresceindiacetateN-succinimidyl ester (CFSE)-labeled CD56+cells was analyzed by flowcytometry after the co-culture with CD1a+or CD83+DC.ResultsDecidual CD1a+cells show less mature phenotype with no expression ofCD197, lower expression of CD80 and CD86 and higher expression ofCD206 and CD195 in comparison to CD83+cells. Interleukin (IL)-15,interferon-cand tumor necrosis factor-aproductions were higher inimmature than mature DC, whereas IL-10 and IL-18 were equally pro-duced in both subpopulations. Immature DC increase perforin, FasL andTRAIL protein expression and proliferation of NK cells, but decreasetheir intracellular IL-15 production. Mature DC caused less efficient pro-liferation of NK cells, and did not affect cytokine and cytolytic mediatorexpression.ConclusionThese results suggest that decidual CD1a+cells regulate and shape NKcell function more profoundly than CD83+cells in decidua.ORIGINAL ARTICLEAmerican Journal of Reproductive Immunology59(2008) 433–445ª2008 The AuthorsJournal compilationª2008 Blackwell Munksgaard433
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
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Naslov časopisaAmerican Journal of Reproductive Immunology
Brojčani podacivol. 59, br. 5, str. 433-445
p-ISSN1046-7408
DOIhttps://doi.org/10.1111/j.1600-0897.2008.00599.x
URN:NBNurn:nbn:hr:184:737446
Datum objave publikacije2008-04-09
URL dokumentahttps://onlinelibrary.wiley.com/doi/10.1111/j.1600-0897.2008.00599.x
Vrsta resursaTekst
Prava pristupaOgraničen pristup
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Datum i vrijeme pohrane2023-06-30 09:04:27