prikaz prve stranice dokumenta Current incidence, severity, and management of veno-occlusive disease/sinusoidal obstruction syndrome in adult allogeneic HSCT recipients: an EBMT Transplant Complications Working Party study
  Preuzmi
PDF 909.97 KB
Znanstveni rad - Izvorni znanstveni rad
Current incidence, severity, and management of veno-occlusive disease/sinusoidal obstruction syndrome in adult allogeneic HSCT recipients: an EBMT Transplant Complications Working Party study
Bone Marrow Transplantation, 58 (2023), 11; 1209-1214. https://doi.org/10.1038/s41409-023-02077-2
Ruutu, Tapani; Peczynski, Christophe; Houhou, Mohamed; Polge, Emmanuelle; Mohty, Mohamad; Kröger, Nicolaus; Moiseev, Ivan; Penack, Olaf; Salooja, Nina; Schoemans, Hélène; Duarte, Rafael F.; Schroeder, Thomas; Passweg, Jakob; Wulf, Gerald G.; Ganser, Arnold; Sica, Simona; Arat, Mutlu; Salmenniemi, Urpu; Broers, Annoek E. C.; Bourhis, Jean Henri; Rambaldi, Alessandro; Maertens, Johan; Halaburda, Kazimierz; Zuckerman, Tsila; Labussière-Wallet, Hélène; Basak, Grzegorz; Koenecke, Christian; Perić, Zinaida Više autora...

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Citirajte ovaj rad

Ruutu, T., Peczynski, C., Houhou, M., Polge, E., Mohty, M., Kröger, N. ... Perić, Z. (2023). Current incidence, severity, and management of veno-occlusive disease/sinusoidal obstruction syndrome in adult allogeneic HSCT recipients: an EBMT Transplant Complications Working Party study. Bone Marrow Transplantation, 58. (11), 1209-1214. doi: 10.1038/s41409-023-02077-2

Ruutu, Tapani, et al. "Current incidence, severity, and management of veno-occlusive disease/sinusoidal obstruction syndrome in adult allogeneic HSCT recipients: an EBMT Transplant Complications Working Party study." Bone Marrow Transplantation, vol. 58, br. 11, 2023, str. 1209-1214. https://doi.org/10.1038/s41409-023-02077-2

Ruutu, Tapani, Christophe Peczynski, Mohamed Houhou, Emmanuelle Polge, Mohamad Mohty, Nicolaus Kröger, Ivan Moiseev, et al. "Current incidence, severity, and management of veno-occlusive disease/sinusoidal obstruction syndrome in adult allogeneic HSCT recipients: an EBMT Transplant Complications Working Party study." Bone Marrow Transplantation 58, br. 11 (2023): 1209-1214. https://doi.org/10.1038/s41409-023-02077-2

Ruutu, T., et al. (2023) 'Current incidence, severity, and management of veno-occlusive disease/sinusoidal obstruction syndrome in adult allogeneic HSCT recipients: an EBMT Transplant Complications Working Party study', Bone Marrow Transplantation, 58(11), str. 1209-1214. doi: 10.1038/s41409-023-02077-2

Ruutu T, Peczynski C, Houhou M, Polge E, Mohty M, Kröger N, i sur.. Current incidence, severity, and management of veno-occlusive disease/sinusoidal obstruction syndrome in adult allogeneic HSCT recipients: an EBMT Transplant Complications Working Party study. Bone Marrow Transplantation [Internet]. 12.08.2023. [pristupljeno 30.11.2024.];58(11):1209-1214. doi: 10.1038/s41409-023-02077-2

T. Ruutu, et al., "Current incidence, severity, and management of veno-occlusive disease/sinusoidal obstruction syndrome in adult allogeneic HSCT recipients: an EBMT Transplant Complications Working Party study", Bone Marrow Transplantation, vol. 58, br. 11, str. 1209-1214, Kolovoz 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:163794. [Citirano: 30.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:163794
Podaci o radu
Naslov (engleski)Current incidence, severity, and management of veno-occlusive disease/sinusoidal obstruction syndrome in adult allogeneic HSCT recipients: an EBMT Transplant Complications Working Party study
AutorTapani Ruutu
AutorChristophe Peczynski
AutorMohamed Houhou
AutorEmmanuelle Polge
AutorMohamad Mohty
AutorNicolaus Kröger
AutorIvan Moiseev
AutorOlaf Penack
AutorNina Salooja
AutorHélène Schoemans
AutorRafael F. Duarte
AutorThomas Schroeder
AutorJakob Passweg
AutorGerald G. Wulf
AutorArnold Ganser
AutorSimona Sica
AutorMutlu Arat
AutorUrpu Salmenniemi
AutorAnnoek E. C. Broers
AutorJean Henri Bourhis
AutorAlessandro Rambaldi
AutorJohan Maertens
AutorKazimierz Halaburda
AutorTsila Zuckerman
AutorHélène Labussière-Wallet
AutorGrzegorz Basak
AutorChristian Koenecke
AutorZinaida Perić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
The current incidence, diagnostic policy, management, and outcome of VOD/SOS at EBMT centers were studied. All centers that had performed allogeneic HSCTs in adult patients within one defined year were invited to the study. Seventy-one centers participated with a total of 2886 allogeneic transplantations and 93 cases of VOD/SOS in 2018. The cumulative incidence of VOD/SOS at day 21 was 1.8% and at day 100 2.4%. Of 67 cases with detailed data, 52 were classical and 15 (22%) late onset (>day 21). According to the EBMT criteria, 65/67 patients had at least two VOD/SOS risk factors. The severity grades were: mild 0, moderate 3, severe 29, very severe 35. Fifty-four patients were treated with defibrotide. VOD/SOS resolved in 58% of the patients, 3/3 with moderate, 22/28 with severe, and 12/33 with very severe grade (p < 0.001). By day 100, 57% of the patients were alive; 3/3 with moderate, 22/29 with severe, and 13/35 with very severe VOD/SOS (p = 0.002). In conclusion, the incidence of VOD/SOS was low. Severe and very severe grades dominated. Very severe grade predicted poor outcome compared to severe grade further supporting the concept of early diagnosis and treatment to avoid a dismal outcome.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBone Marrow Transplantation
Brojčani podacivol. 58, br. 11, str. 1209-1214
p-ISSN0268-3369
e-ISSN1476-5365
DOIhttps://doi.org/10.1038/s41409-023-02077-2
URN:NBNurn:nbn:hr:105:163794
Datum objave publikacije2023-08-12
URL dokumentahttps://www.nature.com/articles/s41409-023-02077-2
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-08-26 08:13:18