prikaz prve stranice dokumenta Compensated Advanced Chronic Liver Disease and Steatosis in Patients with Type 2 Diabetes as Assessed through Shear Wave Measurements and Attenuation Measurements
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Compensated Advanced Chronic Liver Disease and Steatosis in Patients with Type 2 Diabetes as Assessed through Shear Wave Measurements and Attenuation Measurements
Biomedicines, 12 (2024), 2; 323. https://doi.org/10.3390/biomedicines12020323
Barišić-Jaman, Mislav; Milošević, Marko; Skurla, Viktoria; Dohoczky, David; Stojić, Josip; Dinjar Kujundžić, Petra; Cigrovski Berković, Maja; Majić-Tengg, Ana; Matijaca, Ana; Lucijanić, Tomo; Kardum-Pejić, Mirjana; Pandžić Jakšić, Vlatka; Marušić, Srećko; Grgurević, Ivica

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

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Barišić Jaman, M., Milošević, M., Skurla, V., Dohoczky, D., Stojić, J., Dinjar Kujundžić, P. ... Grgurević, I. (2024). Compensated Advanced Chronic Liver Disease and Steatosis in Patients with Type 2 Diabetes as Assessed through Shear Wave Measurements and Attenuation Measurements. Biomedicines, 12. (2). doi: 10.3390/biomedicines12020323

Barišić Jaman, Mislav, et al. "Compensated Advanced Chronic Liver Disease and Steatosis in Patients with Type 2 Diabetes as Assessed through Shear Wave Measurements and Attenuation Measurements." Biomedicines, vol. 12, br. 2, 2024. https://doi.org/10.3390/biomedicines12020323

Barišić Jaman, Mislav, Marko Milošević, Viktoria Skurla, David Dohoczky, Josip Stojić, Petra Dinjar Kujundžić, Maja Cigrovski Berković, et al. "Compensated Advanced Chronic Liver Disease and Steatosis in Patients with Type 2 Diabetes as Assessed through Shear Wave Measurements and Attenuation Measurements." Biomedicines 12, br. 2 (2024). https://doi.org/10.3390/biomedicines12020323

Barišić Jaman, M., et al. (2024) 'Compensated Advanced Chronic Liver Disease and Steatosis in Patients with Type 2 Diabetes as Assessed through Shear Wave Measurements and Attenuation Measurements', Biomedicines, 12(2). doi: 10.3390/biomedicines12020323

Barišić Jaman M, Milošević M, Skurla V, Dohoczky D, Stojić J, Dinjar Kujundžić P, i sur.. Compensated Advanced Chronic Liver Disease and Steatosis in Patients with Type 2 Diabetes as Assessed through Shear Wave Measurements and Attenuation Measurements. Biomedicines [Internet]. 30.01.2024. [pristupljeno 26.11.2024.];12(2). doi: 10.3390/biomedicines12020323

M. Barišić Jaman, et al., "Compensated Advanced Chronic Liver Disease and Steatosis in Patients with Type 2 Diabetes as Assessed through Shear Wave Measurements and Attenuation Measurements", Biomedicines, vol. 12, br. 2, Siječanj 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:663352. [Citirano: 26.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:663352
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Naslov (engleski)Compensated Advanced Chronic Liver Disease and Steatosis in Patients with Type 2 Diabetes as Assessed through Shear Wave Measurements and Attenuation Measurements
AutorMislav Barišić-Jaman
AutorMarko Milošević
AutorViktoria Skurla
AutorDavid Dohoczky
AutorJosip Stojić
AutorPetra Dinjar Kujundžić
AutorMaja Cigrovski Berković
AutorAna Majić-Tengg
AutorAna Matijaca
AutorTomo Lucijanić
AutorMirjana Kardum-Pejić
AutorVlatka Pandžić Jakšić
AutorSrećko Marušić
AutorIvica Grgurević
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Patients with type 2 diabetes (T2D) are at risk of developing metabolic dysfunction-associated steatotic liver disease (MASLD). We investigated the prevalence of compensated advanced chronic liver disease (cACLD) and steatosis in patients with T2D using the new non-invasive diagnostic methods of shear wave measurements (SWMs) and attenuation (ATT) measurements in comparison with those of vibration-controlled transient elastography (VCTE) and the controlled attenuation parameter (CAP), which served as the reference methods. Among 214 T2D patients, steatosis at any grade and cACLD were revealed in 134 (62.6%) and 19 (8.9%) patients, respectively. SWMs showed a high correlation with VCTE (Spearman’s ρ = 0.641), whereas SWMs produced lower (mean of −0.7 kPa) liver stiffness measurements (LSMs) overall. At a LSM of >11.0 kPa (Youden), SWMs had an AUROC of 0.951 that was used to diagnose cACLD (defined as a LSM of >15 kPa through VCTE) with 84.2% sensitivity and 96.4% specificity. The performance of ATT measurements in diagnosing liver steatosis at any grade (defined as the CAP of ≥274 dB/m) was suboptimal (AUROC of 0.744 at the ATT measurement cut-off of >0.63 dB/cm/MHz (Youden) with 59% sensitivity and 81.2% specificity). In conclusion, the prevalence of liver steatosis and previously unrecognized cACLD in patients with T2D is high and SWMs appear to be a reliable diagnostic method for this purpose, whereas further investigation is needed to optimize the diagnostic performance of ATT measurements.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBiomedicines
Brojčani podacivol. 12, br. 2, 323
e-ISSN2227-9059
DOIhttps://doi.org/10.3390/biomedicines12020323
URN:NBNurn:nbn:hr:105:663352
Datum objave publikacije2024-01-30
URL dokumentahttps://www.mdpi.com/2227-9059/12/2/323
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-11-13 15:13:26