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Assessing Symptomatic Hypocalcemia Risk After Total Thyroidectomy: A Prospective Study
International Archives of Otorhinolaryngology, 28 (2024), 01; e12-e21. https://doi.org/10.1055/s-0043-1777450
Košec, Andro; Gašić, Ana; Hergešić, Filip; Rašić, Ivan; Košec, Vesna; Bedeković, Vladimir

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

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Košec, A., Gašić, A., Hergešić, F., Rašić, I., Košec, V. i Bedeković, V. (2024). Assessing Symptomatic Hypocalcemia Risk After Total Thyroidectomy: A Prospective Study. International Archives of Otorhinolaryngology, 28. (01), e12-e21. doi: 10.1055/s-0043-1777450

Košec, Andro, et al. "Assessing Symptomatic Hypocalcemia Risk After Total Thyroidectomy: A Prospective Study." International Archives of Otorhinolaryngology, vol. 28, br. 01, 2024, str. e12-e21. https://doi.org/10.1055/s-0043-1777450

Košec, Andro, Ana Gašić, Filip Hergešić, Ivan Rašić, Vesna Košec i Vladimir Bedeković. "Assessing Symptomatic Hypocalcemia Risk After Total Thyroidectomy: A Prospective Study." International Archives of Otorhinolaryngology 28, br. 01 (2024): e12-e21. https://doi.org/10.1055/s-0043-1777450

Košec, A., et al. (2024) 'Assessing Symptomatic Hypocalcemia Risk After Total Thyroidectomy: A Prospective Study', International Archives of Otorhinolaryngology, 28(01), str. e12-e21. doi: 10.1055/s-0043-1777450

Košec A, Gašić A, Hergešić F, Rašić I, Košec V, Bedeković V. Assessing Symptomatic Hypocalcemia Risk After Total Thyroidectomy: A Prospective Study. International Archives of Otorhinolaryngology [Internet]. 05.02.2024. [pristupljeno 26.12.2024.];28(01):e12-e21. doi: 10.1055/s-0043-1777450

A. Košec, A. Gašić, F. Hergešić, I. Rašić, V. Košec i V. Bedeković, "Assessing Symptomatic Hypocalcemia Risk After Total Thyroidectomy: A Prospective Study", International Archives of Otorhinolaryngology, vol. 28, br. 01, str. e12-e21, Veljača 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:387369. [Citirano: 26.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:387369
Podaci o radu
Naslov (engleski)Assessing Symptomatic Hypocalcemia Risk After Total Thyroidectomy: A Prospective Study
AutorAndro Košec
AutorAna Gašić
AutorFilip Hergešić
AutorIvan Rašić
AutorVesna Košec
AutorVladimir Bedeković
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA OTORINOLARINGOLOGIJU I KIRURGIJU GLAVE I VRATA)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Otorinolaringologija
Sažetak (engleski)
Introduction The most common postoperative complication of total thyroidectomy is hypocalcemia, usually monitored using serum parathyroid hormone and calcium values. Objective To identify the most accurate predictors of hypocalcemia, construct a risk assesment algorithm and analyze the impact of using several calcium correction formulas in practice. Methods A prospective, single-center, non-randomized longitudinal cohort study on 205 patients undergoing total thyroidectomy. Parathyroid hormone, serum, and ionized calcium were sampled post-surgery, with the presence of symptomatic or laboratory-verified asymptomatic hypocalcemia designated as primary outcome measures. Results Parathyroid hormone sampled on the first postoperative day was the most sensitive predictor of symptomatic hypocalcemia development (sensitivity 80.22%, cut-off value ≤2.03 pmol/L). A combination of serum calcium and parathyroid concentration sampled on the first postoperative day predicted the development of hypocalcemia during recovery with the highest sensitivity and specificity (94% sensitivity, cut-off ≤2.1 mmol/L, and 89% specificity, cut-off ≤1.55 pmol/L, respectively). The use of algorithms and correction formulas did not improve the accuracy of predicting symptomatic or asymptomatic hypocalcemia. Conclusions The most sensitive predictor of symptomatic hypocalcemia present on the fifth postoperative day was PTH sampled on the first postoperative day. The need for algorithms and correction formulas is limited.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaInternational Archives of Otorhinolaryngology
Brojčani podacivol. 28, br. 01, str. e12-e21
p-ISSN1809-9777
e-ISSN1809-4864
DOIhttps://doi.org/10.1055/s-0043-1777450
URN:NBNurn:nbn:hr:105:387369
Datum objave publikacije2024-02-05
URL dokumentahttp://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1777450
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-12-02 10:42:10