Pulmonary Embolism (PE) is a grave medical emergency that has the potential to be fatal. It is caused by the complete or partial obstruction of the pulmonary arteries and or its branches and may lead to acute life-threatening but potentially reversible right ventricular failure. The most common cause of pulmonary embolism is Venous Thromboembolism. PE interferes with both the circulation and gas exchange. Right ventricular failure due to pressure overload is considered the primary cause of death. Pulmonary embolism is a very difficult diagnosis to make because the signs and symptoms are often nonspecific. PE is not a disease on its own per say, rather it is a complication of other systemic hypercoagulability states. In addition to standard diagnostic tools such as D-dimers, compression ultrasonography and CT, today echocardiography is also used in diagnosing PE. Right ventricular assessments are challenging due to the complex 3-dimensional geometric structure of the ventricle. The dysfunction of the right ventricle directly affects the prognosis in patients with PE so being able to quantify this dysfunction and detect it helps in the choice of treatment. Echocardiography is excellent for assessing right ventricle dysfunction, and as such can help greatly in deciding which treatment to give to which patient and quantify the severity of illness. Moreover, the ESC has officially recommended the use of echocardiography in high risk patients for the diagnosis of pulmonary embolism and in the choice of thrombolysis.