For successful leadership, it is necessary to know and understand people with whom we work. One of the disciplines that study man and man's behavior is psychoanalysis. Psychoanalysis with its psychodynamic view of the world and man is studying psychological forces in the inner world of man and how they affect his behavior. Freud has primarily developed psychoanalysis as a method of treating mental disorders, but psychoanalysis concepts can be applied much more widely. So psychoanalysis is applied to the study of art, politics, organization, society, etc. Manfred Kets de Vries is a psychoanalyst who has greatly contributed to the understanding of human behavior within the organization. Relying on the work of Kets de Vries, this paper explores how the inner world of man, his emotions, fantasies and desires affect his life within the organization. Both successful and unsuccessful leaders and entrepreneurs are fascinated by a large number of people and psychoanalysts. Psychoanalysis provides an explanation as to how pathological personality traits such as hypomania and alexithymia lead to dysfunctional leadership. Special emphasis is given to the role of narcissism in leadership and the difference between healthy and pathological narcissism. One chapter deals with Alexander the Great as one of the most famous leaders in history and lessons we can learn by studying his conquests. At the end of the paper, there is discussion about leadership and globalization and what psychoanalysis can offer in the creation of successful leaders.