Carbon monoxide (CO) intoxications are amongst the leading causes of death when it comes to accidental poisonings. Although they are relatively rare (while searching through the archive in Zagreb's Institute of Forensic Medicine, there were only 30 cases found in the last 5 years), they represent significant danger in everyday life. Carbon monoxide is an odorless, colorless, non-irritating gas, slightly lighter than air. It blocks respiration at the mitochondrial level. Usually it is a product of incomplete combustion of organic compounds. That being said, it is clear that the main sources of these poisonings are car motors, housefires, stoves and water heaters, but also smoking cigarettes and cigars, which can significantly raise the percentage of carboxyhemoglobin (COHb). It is known that carbon monoxide is 200-300 times more likely to bind to unsaturated hemoglobin than oxygen. These intoxications are dangerous, as there are no clear signs and symptoms which would alert the person to leave the place of danger. At autopsy, the most striking appearance is the color of the skin, which is commonly described as cherry-red. Spectrophotometry of carbon monoxide is usually done to confirm the diagnosis. At the very beginning of 21st century carbon monoxide poisonings became an enormously popular way to end one's own life, especially in the Far East. In conclusion, carbon monoxide intoxications are one of the leading causes of accidental deaths, but may also be the method of committing suicide.