The aim of this study was to assess the number of ultrasound examinations needed for the medical student to reach a reasonable level of proficiency in ultrasonic evaluation of central venous pressure (CVP), and to check the value of different inferior vena cava (IVC) assessment methods in CVP estimation. The diameter of the IVC in the inspiration and the expiration was evaluated and measured by the epigastric and the intercostal approach, showing the transverse and longitudinal section in the B and M modes. Without insight into the value of CVP and the results of other examiner, a student and a specialist experienced in ultrasonography examined each patient. CVP was predicated by free evaluation and by the reading from the ASE table based on the measurements. Neither examiner had insight into other examiners results nor had the examiners insight into the CVP measured via the central venous catheter. Thirty patients were included in the study. After the first 15 patients, the agreement between the student’s and the specialist’s categorization of CVP according to the Cohen’s kappa coefficient was in a slight degree for both the free evaluation of CVP and B and M mode. After the examination of the next 15 patients, the agreement was in the fair degree for both the free evaluation of CVP and B and M mode. After 30 ultrasound examinations the student improved his capabilities of assessing CVP based on ultrasonic evaluation of IVC. Experienced specialist, as well as student, wasn’t efficient in accurate assessment of CVP by this method in the population of adult intensive care unit patients that, besides volume status, had other factors that influence the diameter of IVC. Therefore it is not possible to assess the student’s capabilities of using this method with certainty after examining 30 patients. The free estimate was found to be less accurate in CVP prediction than the measurement of the IVC diameter. With the respect to the CVP prediction, no significant differences were found between the measurements in the longitudinal or transverse plane as well as between examinations from the epigastrium or intercostal spaces. This was found in both B and M mode.