Advances in technology, the advent of computers and the Internet have led to a paradigm shift in many scientific disciplines, including pathology. The ability to store a physical tissue preparation on an electronic medium has led to a revolution in processing and analysis of pathohistological slides. The ease of manipulation of virtual slides helped in improving the diagnostic process and seeking a second opinion (consultation), enabled rapid development of telepathology and simplified re-evaluation, archiving, sharing and education. Also, virtual slides are subject to automatic software analysis based on machine learning, a branch of artificial intelligence that deals with designing algorithms that improve their efficiency based on empirical data. Such systems facilitate the workflow of the pathologist, and can potentially recognize patterns in pathologic specimens that a human cannot detect. Digital pathology has made it possible to share slides online and consult with pathologists from all over the world in real time. The introduction of computers and the Internet in less developed countries opens the possibility of high quality diagnostics, which experts can participate in from the comfort of their homes.