Marine animal bites occur around the world. The estimate of the number of bites is based on assumptions because the exact number is impossible to determine. When it comes to marine animals and bites, due to the specific morphology of the species, stings are an indispensable part. The Adriatic Sea is rich in life, and about 20 species of fish from different families are considered poisonous. It is important to note that most marine animal attacks are the result of self-defense. Eels and sharks are among the animals that have a dangerous bite. The incidence of eel bites is unknown. In the past 120 years, in the Croatian part of the Adriatic, 21 shark attacks on humans have been recorded, and 14 of them have resulted in death. Injuries that occur during a bite depend on the location and size of the bite and are treated accordingly. There are also several species of poisonous animals in the Adriatic Sea. Their common characteristic is that they produce a thermolabile poison that is effectively inactivated at high temperatures and leaves no serious consequences. Prophylactic administration of antibiotics is justified to prevent secondary wound infections. The consequences of their stings most often affect careless swimmers and fishermen. Jellyfish and sea anemones are classified in the phylum Cnidaria. Although rare, the most severe complication of their sting is the onset of anaphylactic shock. Prevention is key to reduce the number of stings and bites of marine animals and it is achieved by educating the population.