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The Role of Lipid Profile as an Independent Predictor of Non-alcoholic Steatosis and Steatohepatitis in Morbidly Obese Patients
Frontiers in Cardiovascular Medicine, 8 (2021); 682352. https://doi.org/10.3389/fcvm.2021.682352
Ganjooei, Narges Ashraf; Jamialahmadi, Tannaz; Nematy, Mohsen; Jangjoo, Ali; Goshayeshi, Ladan; Khadem-Rezaiyan, Majid; Reiner, Željko; Alidadi, Mona; Markin, Alexander M.; Sahebkar, Amirhossein

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Citirajte ovaj rad

Ganjooei, N. A., Jamialahmadi, T., Nematy, M., Jangjoo, A., Goshayeshi, L., Khadem Rezaiyan, M. ... Sahebkar, A. (2021). The Role of Lipid Profile as an Independent Predictor of Non-alcoholic Steatosis and Steatohepatitis in Morbidly Obese Patients. Frontiers in Cardiovascular Medicine, 8.. doi: 10.3389/fcvm.2021.682352

Ganjooei, Narges Ashraf, et al. "The Role of Lipid Profile as an Independent Predictor of Non-alcoholic Steatosis and Steatohepatitis in Morbidly Obese Patients." Frontiers in Cardiovascular Medicine, vol. 8, 2021. https://doi.org/10.3389/fcvm.2021.682352

Ganjooei, Narges Ashraf, Tannaz Jamialahmadi, Mohsen Nematy, Ali Jangjoo, Ladan Goshayeshi, Majid Khadem Rezaiyan, Željko Reiner, Mona Alidadi, Alexander M. Markin i Amirhossein Sahebkar. "The Role of Lipid Profile as an Independent Predictor of Non-alcoholic Steatosis and Steatohepatitis in Morbidly Obese Patients." Frontiers in Cardiovascular Medicine 8 (2021). https://doi.org/10.3389/fcvm.2021.682352

Ganjooei, N. A., et al. (2021) 'The Role of Lipid Profile as an Independent Predictor of Non-alcoholic Steatosis and Steatohepatitis in Morbidly Obese Patients', Frontiers in Cardiovascular Medicine, 8. doi: 10.3389/fcvm.2021.682352

Ganjooei NA, Jamialahmadi T, Nematy M, Jangjoo A, Goshayeshi L, Khadem Rezaiyan M, i sur.. The Role of Lipid Profile as an Independent Predictor of Non-alcoholic Steatosis and Steatohepatitis in Morbidly Obese Patients. Frontiers in Cardiovascular Medicine [Internet]. 31.05.2021. [pristupljeno 30.11.2024.];8. doi: 10.3389/fcvm.2021.682352

N. A. Ganjooei, et al., "The Role of Lipid Profile as an Independent Predictor of Non-alcoholic Steatosis and Steatohepatitis in Morbidly Obese Patients", Frontiers in Cardiovascular Medicine, vol. 8, Svibanj 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:088134. [Citirano: 30.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:088134
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Naslov (engleski)The Role of Lipid Profile as an Independent Predictor of Non-alcoholic Steatosis and Steatohepatitis in Morbidly Obese Patients
AutorNarges Ashraf Ganjooei
AutorTannaz Jamialahmadi
AutorMohsen Nematy
AutorAli Jangjoo
AutorLadan Goshayeshi
AutorMajid Khadem-Rezaiyan
AutorŽeljko Reiner
AutorMona Alidadi
AutorAlexander M. Markin
AutorAmirhossein Sahebkar
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Background and Aims: Obesity is one of the major health problems worldwide. Morbid obesity (body mass index >40 kg/m2 or over 35 with a comorbidity) is associated, apart from other diseases, with an increased risk of non-alcoholic fatty liver disease (NAFLD). Moreover, dyslipidemia is an important comorbidity that is frequently found in NAFLD patients. The aim of this study was to analyze whether serum lipids in morbidly obese patients are associated with the spectrum of NAFLD. ----- Methods: Total serum cholesterol, LDL cholesterol, HDL cholesterol, non-HDL cholesterol, VLDL, and triglycerides were analyzed in 90 morbidly obese patients. The association of lipid profile parameters with histopathological, elastographic, and sonographic indices of NAFLD, non-alcoholic steatohepatitis (NASH), and liver fibrosis were explored. ----- Results: The mean levels of serum total cholesterol, LDL-C, and non-HDL cholesterol in patients with positive histology for liver steatosis and NASH were significantly higher than those in patients with negative histology. None of the indices showed a strong association with NAFLD, NASH, or liver fibrosis after adjustment for potential confounders. ----- Conclusion: A slight predictive value of lipid profile is not sufficiently enough to use solely as a non-invasive test in predicting NASH or liver fibrosis.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaFrontiers in Cardiovascular Medicine
Brojčani podacivol. 8, 682352
e-ISSN2297-055X
DOIhttps://doi.org/10.3389/fcvm.2021.682352
URN:NBNurn:nbn:hr:105:088134
Datum objave publikacije2021-05-31
URL dokumentahttps://www.frontiersin.org/articles/10.3389/fcvm.2021.682352/full
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2021-12-16 09:43:00