Pelvic inflammatory disease (PID) is a clinical syndrome that includes inflammation of one or more pelvic reproductive organs. Infection is the main cause of the inflammation and it usually spreads ascendingly from lower to upper portions of female genital system. Diagnosis is commonly established in fertile women who were exposed to infective agents during sexual intercourse. Disease mostly presents in acute form and, depending on severity of symptoms, management of the disease can occur in outpatient or inpatient settings. The basic clinical management of PID is antibiotic therapy. However, in some cases surgical intervention is required. The aim of this retrospective study was to demonstrate epidemiological characteristics of surgically treated patients with acute PID from Clinical department of obstetrics and gynaecology, University Hospital „Sveti Duh“ (September 1st, 2009 – September 1st, 2019). Following assessment of surgical data records and hospital informatic system (HIS) data, 92 patients matched the inclusion (hospital admission under clinical presentation of acute PID and subsequent surgical treatment) and exclusion criteria (chronic PID, hospital admission due to elective surgical procedure). Epidemiological information displayed in this research was also withdrawn from HIS. The results showed that acute PID which required surgical intervention presented in 39.13% of cases between the age of 35 and 44. The majority of patients were A+ blood group (39.13%) whereas most of the cases occurred during July (19.58%). At the moment of diagnosis, 42.39% of women were nulliparous without any noted abortions (spontaneous or induced). Evaluation of PID symptoms, regarding the certain phase of menstrual cycle (MC), pointed out that first manifestations most frequently occurred during the secretion phase (39.08%) and moreover, during the same phase hospital admission was the most required (48.27%). Furthermore, 67.82% of patients needed medical assistance during the same phase of MC in which symptoms occurred. The analysis of correlation between the age of women and duration of hospital treatment showed no statistical significance. In conclusion, taking into account that PID can cause permanent damage on reproductive system and female fertility, this study attempts to emphasize certain epidemiological characteristic of affected patients which could be impactful in diagnosis and treatment.