Chronic obstructive pulmonary disease (COPD) is a progressive and chronic lung disease characterized by obstructive airway disorders, decreased respiratory area, and systemic inflammation with a pronounced pulmonary component. Cardiovascular disease (CVD) is often present in the COPD population. CVDs are the most significant comorbidity in people with COPD, due to their frequency but also due to the association with a poorer outcome. People who suffer from COPD with COPD have a higher risk of hospitalization, longer hospital stays and, ultimately, higher mortality. The most common CVDs that occur with COPD are hypertension, ischemic heart disease, heart failure, pulmonary hypertension, peripheral arterial disease, and arrhythmias, among which atrial fibrillation is the most common. Their simultaneous occurrence is partly explained by common risk factors, primarily smoking, but there are many pathophysiological mechanisms that affect the development of CVD in patients with COPD. The association is still being investigated, and the main goal is to devise targeted therapy to prevent the development of both diseases. In addition to being a major health problem for sufferers, it is also a major financial burden on the health care system. That is why this paper emphasizes the importance of active search and timely treatment of CVD in people with COPD. Levels of early detection and appropriate treatment of CVD as a comorbidity of COPD are still not satisfactory. The reason for this can be found in the lack of clear protocols for access to CVD in COPD patients, but also in the absence of therapeutic guidelines for the treatment of CVD in patients with COPD. Education is extremely important, it has been proven that doctors prescribe significantly fewer drugs for CVD in COPD patients than is the case in patients suffering exclusively from CVD. The main cause is the fear of worsening the underlying disease, primarily the onset of bronchospasm. This insufficient treatment of CVD in COPD patients directly affects the deterioration of quality of life and increased mortality.