Repair of ventral hernias is a big challenge in modern surgery. Ventral hernias are induced by many factors, such as body mass, history of laparotomy, gender, ratio of collagen type I and type III, number of pregnancies. Most of the time, the treatment of ventral hernias is done by an elective surgical procedure with few contraindications such as intolerance to anesthesia or a bad general condition of the patient. The hardship which is made by the organ protrusion can be soothed by wearing a hernia belt, however, the only permanent solution is a surgical procedure. The initial approach of a simple defect quilting in the fascia was leading to a high recurrence rate. Mending of the huge stomach defects is sometimes a complex procedure so in order to develop new techniques a big number of prosthetic materials was developed. The first prosthetic meshes which were used in the mending of defects showed a big rejection rates, and the same holds true for the infection rates. Meshes have continuously been developed and are nowadays a standard repair technique for stomach defects. There are more than seventy types of medical meshes on the market including biological, synthetic resorptive and synthetic no-resorptive. The golden standard in the treatment of ventral hernia is the Rives-Stopp method. Techniques such as Ramirez and da Silva are often used as well. However, a rise in popularity has been noted for the minimally invasive methods which are divided according to the placement of the mesh. They are classified into retro-muscular, suprafascial and intraperitoneal methods. Retro-muscular methods are: MILOS, eMILOS, TAPP, MIC Rives Stapler Repair, eTEP, etc. Suprafascial methods for the treatment of ventral hernias are: TESLA,SCOLA, ELAR. Intraperitoneal methods include IPOM and LIRA. When choosing the surgical method it is necessary to determine the general condition of the patient, available materials (surgical meshes) and the general experience of the surgeon in the treatment of complex stomach defects.