prikaz prve stranice dokumenta HDL-apoA-II Is Strongly Associated with 1-Year Mortality in Acute Heart Failure Patients
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HDL-apoA-II Is Strongly Associated with 1-Year Mortality in Acute Heart Failure Patients
Biomedicines, 10 (2022), 7; 1668. https://doi.org/10.3390/biomedicines10071668
Klobučar, Iva; Degoricija, Vesna; Potočnjak, Ines; Trbušić, Matias; Pregartner, Gudrun; Berghold, Andrea; Fritz-Petrin, Eva; Habisch, Hansjörg; Madl, Tobias; Frank, Saša

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

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Klobučar, I., Degoricija, V., Potočnjak, I., Trbušić, M., Pregartner, G., Berghold, A. ... Frank, S. (2022). HDL-apoA-II Is Strongly Associated with 1-Year Mortality in Acute Heart Failure Patients. Biomedicines, 10. (7). doi: 10.3390/biomedicines10071668

Klobučar, Iva, et al. "HDL-apoA-II Is Strongly Associated with 1-Year Mortality in Acute Heart Failure Patients." Biomedicines, vol. 10, br. 7, 2022. https://doi.org/10.3390/biomedicines10071668

Klobučar, Iva, Vesna Degoricija, Ines Potočnjak, Matias Trbušić, Gudrun Pregartner, Andrea Berghold, Eva Fritz Petrin, Hansjörg Habisch, Tobias Madl i Saša Frank. "HDL-apoA-II Is Strongly Associated with 1-Year Mortality in Acute Heart Failure Patients." Biomedicines 10, br. 7 (2022). https://doi.org/10.3390/biomedicines10071668

Klobučar, I., et al. (2022) 'HDL-apoA-II Is Strongly Associated with 1-Year Mortality in Acute Heart Failure Patients', Biomedicines, 10(7). doi: 10.3390/biomedicines10071668

Klobučar I, Degoricija V, Potočnjak I, Trbušić M, Pregartner G, Berghold A, i sur.. HDL-apoA-II Is Strongly Associated with 1-Year Mortality in Acute Heart Failure Patients. Biomedicines [Internet]. 11.07.2022. [pristupljeno 09.11.2024.];10(7). doi: 10.3390/biomedicines10071668

I. Klobučar, et al., "HDL-apoA-II Is Strongly Associated with 1-Year Mortality in Acute Heart Failure Patients", Biomedicines, vol. 10, br. 7, Srpanj 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:642691. [Citirano: 09.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:642691
Podaci o radu
Naslov (engleski)HDL-apoA-II Is Strongly Associated with 1-Year Mortality in Acute Heart Failure Patients
AutorIva Klobučar
AutorVesna Degoricija
AutorInes Potočnjak
AutorMatias Trbušić
AutorGudrun Pregartner
AutorAndrea Berghold
AutorEva Fritz-Petrin
AutorHansjörg Habisch
AutorTobias Madl
AutorSaša Frank
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
The prognostic value of the subset of high-density lipoprotein (HDL) particles containing apolipoprotein (apo)A-II (HDL-apoA-II) in acute heart failure (AHF) remains unexplored. In this study, baseline serum levels of HDL-apoA-II (total and subfractions 1–4) were measured in 315 AHF patients using NMR spectroscopy. The mean patient age was 74.2 ± 10.5 years, 136 (43.2%) were female, 288 (91.4%) had a history of cardiomyopathy, 298 (94.6%) presented as New York Heart Association class 4, and 118 (37.5%) patients died within 1 year after hospitalization for AHF. Multivariable Cox regression analyses, adjusted for age and sex as well as other clinical and laboratory parameters associated with 1-year mortality in the univariable analyses, revealed a significant inverse association of HDL-apoA-II (hazard ratio (HR) 0.67 per 1 standard deviation (1 SD) increase, 95% confidence interval (CI) 0.47–0.94, p = 0.020), HDL2-apoA-II (HR 0.72 per 1 SD increase, 95% CI 0.54–0.95, p = 0.019), and HDL3-apoA-II (HR 0.59 per 1 SD increase, 95% CI 0.43–0.80, p < 0.001) with 1-year mortality. We conclude that low baseline HDL-apoA-II, HDL2-apoA-II, and HDL3-apoA-II serum levels are associated with increased 1-year mortality in AHF patients and may thus be of prognostic value in AHF.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBiomedicines
Brojčani podacivol. 10, br. 7, 1668
e-ISSN2227-9059
DOIhttps://doi.org/10.3390/biomedicines10071668
URN:NBNurn:nbn:hr:105:642691
Datum objave publikacije2022-07-11
URL dokumentahttps://www.mdpi.com/2227-9059/10/7/1668
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2023-03-01 16:49:30