prikaz prve stranice dokumenta The effects of olanzapine and fluphenazine on plasma cortisol, prolactin and muscle rigidity in schizophrenic patients: a double blind study
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The effects of olanzapine and fluphenazine on plasma cortisol, prolactin and muscle rigidity in schizophrenic patients: a double blind study
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 31 (2007), 2; 399-402. https://doi.org/10.1016/j.pnpbp.2006.10.007
Jakovljević, Miro; Pivac, Nela; Mihaljević-Peleš, Alma; Mustapić, Maja; Relja, Maja; Ljubičić, Đulijano; Marčinko, Darko; Muck-Šeler, Dorotea

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Citirajte ovaj rad

Jakovljević, M., Pivac, N., Mihaljević Peleš, A., Mustapić, M., Relja, M., Ljubičić, Đ. ... Muck Šeler, D. (2007). The effects of olanzapine and fluphenazine on plasma cortisol, prolactin and muscle rigidity in schizophrenic patients: a double blind study. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 31. (2), 399-402. doi: 10.1016/j.pnpbp.2006.10.007

Jakovljević, Miro, et al. "The effects of olanzapine and fluphenazine on plasma cortisol, prolactin and muscle rigidity in schizophrenic patients: a double blind study." Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 31, br. 2, 2007, str. 399-402. https://doi.org/10.1016/j.pnpbp.2006.10.007

Jakovljević, Miro, Nela Pivac, Alma Mihaljević Peleš, Maja Mustapić, Maja Relja, Đulijano Ljubičić, Darko Marčinko i Dorotea Muck Šeler. "The effects of olanzapine and fluphenazine on plasma cortisol, prolactin and muscle rigidity in schizophrenic patients: a double blind study." Progress in Neuro-Psychopharmacology and Biological Psychiatry 31, br. 2 (2007): 399-402. https://doi.org/10.1016/j.pnpbp.2006.10.007

Jakovljević, M., et al. (2007) 'The effects of olanzapine and fluphenazine on plasma cortisol, prolactin and muscle rigidity in schizophrenic patients: a double blind study', Progress in Neuro-Psychopharmacology and Biological Psychiatry, 31(2), str. 399-402. doi: 10.1016/j.pnpbp.2006.10.007

Jakovljević M, Pivac N, Mihaljević Peleš A, Mustapić M, Relja M, Ljubičić Đ, i sur.. The effects of olanzapine and fluphenazine on plasma cortisol, prolactin and muscle rigidity in schizophrenic patients: a double blind study. Progress in Neuro-Psychopharmacology and Biological Psychiatry [Internet]. 30.03.2007. [pristupljeno 28.04.2024.];31(2):399-402. doi: 10.1016/j.pnpbp.2006.10.007

M. Jakovljević, et al., "The effects of olanzapine and fluphenazine on plasma cortisol, prolactin and muscle rigidity in schizophrenic patients: a double blind study", Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 31, br. 2, str. 399-402, Ožujak 2007. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:462924. [Citirano: 28.04.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:462924
Podaci o radu
Naslov (engleski)The effects of olanzapine and fluphenazine on plasma cortisol, prolactin and muscle rigidity in schizophrenic patients: a double blind study
AutorMiro Jakovljević
AutorNela Pivac
AutorAlma Mihaljević-Peleš
AutorMaja Mustapić
AutorMaja Relja
AutorĐulijano Ljubičić
AutorDarko Marčinko
AutorDorotea Muck-Šeler
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Pharmacotherapy of schizophrenia is associated with the stressful side effects. Muscle rigidity causes distress, discomfort and poor compliance. The aim of the study was to determine the relationship between plasma hormones (cortisol and prolactin/PRL) and muscle rigidity in female schizophrenic patients treated with olanzapine or fluphenazine. In a randomized, double-blind 22-weeks study, 12 patients were treated with olanzapine (5-20 mg/day) and 10 patients received fluphenazine (6-21 mg/day). Treatment with olanzapine moderately decreased, while treatment with fluphenazine significantly increased plasma cortisol levels and muscle rigidity. The marked and moderate increase in plasma PRL levels were found in patients treated with fluphenazine and olanzapine, respectively. The results suggested that olanzapine induced moderate neuroendocrine effects and a reduction in rigidity as compared to fluphenazine treatment.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaProgress in Neuro-Psychopharmacology and Biological Psychiatry
Brojčani podacivol. 31, br. 2, str. 399-402
p-ISSN0278-5846
DOIhttps://doi.org/10.1016/j.pnpbp.2006.10.007
URN:NBNurn:nbn:hr:105:462924
Datum objave publikacije2007-03-30
URL dokumentahttps://doi.org/10.1016/j.pnpbp.2006.10.007
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-27 20:04:04