prikaz prve stranice dokumenta Association between red blood cell count and renal function exist in type 1 diabetic patients in the absence of nephropathy
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Association between red blood cell count and renal function exist in type 1 diabetic patients in the absence of nephropathy
Collegium Antropologicum, 37 (2013), 3; 777-782. urn:nbn:hr:105:081422
Bulum, Tomislav; Prkačin, Ingrid; Blaslov, Kristina; Zibar, Karin; Duvnjak, Lea

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

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Bulum, T., Prkačin, I., Blaslov, K., Zibar, K. i Duvnjak, L. (2013). Association between red blood cell count and renal function exist in type 1 diabetic patients in the absence of nephropathy . Collegium Antropologicum, 37. (3), 777-782. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:105:081422

Bulum, Tomislav, et al. "Association between red blood cell count and renal function exist in type 1 diabetic patients in the absence of nephropathy ." Collegium Antropologicum, vol. 37, br. 3, 2013, str. 777-782. https://urn.nsk.hr/urn:nbn:hr:105:081422

Bulum, Tomislav, Ingrid Prkačin, Kristina Blaslov, Karin Zibar i Lea Duvnjak. "Association between red blood cell count and renal function exist in type 1 diabetic patients in the absence of nephropathy ." Collegium Antropologicum 37, br. 3 (2013): 777-782. https://urn.nsk.hr/urn:nbn:hr:105:081422

Bulum, T., et al. (2013) 'Association between red blood cell count and renal function exist in type 1 diabetic patients in the absence of nephropathy ', Collegium Antropologicum, 37(3), str. 777-782. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:105:081422 (Datum pristupa: 17.02.2025.)

Bulum T, Prkačin I, Blaslov K, Zibar K, Duvnjak L. Association between red blood cell count and renal function exist in type 1 diabetic patients in the absence of nephropathy . Collegium Antropologicum [Internet]. 09.2013. [pristupljeno 17.02.2025.];37(3):777-782. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:081422

T. Bulum, I. Prkačin, K. Blaslov, K. Zibar i L. Duvnjak, "Association between red blood cell count and renal function exist in type 1 diabetic patients in the absence of nephropathy ", Collegium Antropologicum, vol. 37, br. 3, str. 777-782, Rujan 2013. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:081422. [Citirano: 17.02.2025.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:081422
Podaci o radu
Naslov (engleski)Association between red blood cell count and renal function exist in type 1 diabetic patients in the absence of nephropathy
Naslov (hrvatski)Povezanost između crvene slike i bubrežne funkcije je prisutna u bolesnika sa šećernom bolešću tipa 1 bez nefropatije
AutorTomislav Bulum
AutorIngrid Prkačin
AutorKristina Blaslov
AutorKarin Zibar
AutorLea Duvnjak
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Anemia is a prevalent finding in patients with type 1 diabetes, particularly in those with albuminuria or reduced renal function. We investigated the relationship between red blood cell count (RBC) and renal function in type 1 diabetic patients with normal or mildly impaired renal function and urinary albumin excretion rate (UAE) < 30 mg/24 h. Study included 313 type 1 diabetic patients with estimated glomerular filtration rate (eGFR) > 60 mL min(-1) 1.73 m(-2), and before any interventions with statins, ACE inhibitors or angiotensin II receptor blockers. UAE was measured from at least two 24-h urine samples. Hemoglobin (Hb), hematocrit (Hct), erythrocytes (E), serum iron and ferritin levels were significantly lower in subjects in the highest quartile of serum creatinine compared to those in lowest quartile (132 vs 148 g/L, 0.39 vs 0.42 L/L, 4.5 vs 4.8 x 10(12)/L, 13 vs 18 micromol/L, and 25 vs 103 microg/L, respectively, for all p < 0.001). Hb and Hct levels were significantly lower in subjects in the highest quartile of UAE compared to those in lowest quartile (135 vs 140 g/L, and 0.40 vs 0.41 L/L, respectively, for all p = 0.03). Finally, those with mildly impaired eGFR had significantly lower levels of Hb, Hct and E compared to those with normal eGFR or hyperfiltrating subjects (133 vs 140 g/L, 0.38 vs 0.41 L/L, and 4.4 vs 4.7 x 10(12)/L, respectively, for all p = 0.01). We have detected that interplay between RBC and renal function parameters occurs even in type 1 diabetic patients with normal or mildly impaired renal function.
Sažetak (hrvatski)
Anemija je česta u bolesnika sa tipom 1 šećerne bolesti, a posebno u onih s albuminurijom ili sniženom bubrežnom funkcijom. Istraživali smo povezanost crvene krvne slike i bubrežne funkcije u bolesnika s tipom 1 šećerne bolesti s normalnom ili blago sniženom bubrežnom funkcijom i razinom albumina u urinu (AU) <30 mg/24 h. Istraživanje je obuhvatilo 313 bolesnika sa tipom 1 šećerne bolesti s urednom ili blago sniženom glomerularnom filtracijom (GF >60 mL/min/1,73 m2), s AU <30 mg/24 h i bez terapije statinima, ACE-inhibitorima ili blokatorima angiotenzinskih receptora. Razina hemoglobina (Hb), hematokrita (Hct), eritrocita (E), serumskog željeza i feritina je bila značajno niža u bolesnika u najvišoj kvartili serumskog kreatinina u odnosu na one u najnižoj kvartili (132 vs 148 g/L, 0.39 vs 0,42 L/L, 4,5 vs 4,8x1012/L, 13 vs 18 μmol/L, i 25 vs 103 μg/L, p<0,001). Razina Hb i Hct je bila značajno niža u bolesnika u najvišoj kvartili AU u odnosu na one u najnižoj kvartili (135 vs 140 g/L, i 0,40 vs 0,41 L/L, p=0,03). Bolesnici s blago sniženom GF su imali značajno nižu razinu Hb, Hct i E u odnosu na one s urednom GF ili hiperfiltracijom (133 vs 140 g/L, 0,38 vs 0,41 L/L, i 4.4 vs 4,7x1012/L, p=0,01). Rezultati istraživanja ukazuju da povezanost crvene krvne slike i bubrežne funkcije postoji već u bolesnika s tipom 1 šećerne bolesti s normalnom ili blago sniženom bubrežnom funkcijom te AU <30 m/24 h.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCollegium Antropologicum
Brojčani podacivol. 37, br. 3, str. 777-782
p-ISSN0350-6134
URN:NBNurn:nbn:hr:105:081422
Datum objave publikacije2013-09
URL dokumentahttps://hrcak.srce.hr/118217
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-27 20:12:45