prikaz prve stranice dokumenta Expression of secreted frizzled-related protein 1 and 3, T-cell factor 1 and lymphoid enhancer factor 1 in clear cell renal cell carcinoma
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Expression of secreted frizzled-related protein 1 and 3, T-cell factor 1 and lymphoid enhancer factor 1 in clear cell renal cell carcinoma
Pathology Oncology Research, 19 (2013), 3; 545-551. https://doi.org/10.1007/s12253-013-9615-3
Nikuševa-Martić, Tamara; Šerman, Ljiljana; Zeljko, Martina; Vidas, Željko; Gašparov, Slavko; Zeljko, Hrvojka Marija; Kosović, Marin; Pećina-Šlaus, Nives

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Citirajte ovaj rad

Nikuševa Martić, T., Šerman, Lj., Zeljko, M., Vidas, Ž., Gašparov, S., Zeljko, H. M. ... Pećina Šlaus, N. (2013). Expression of secreted frizzled-related protein 1 and 3, T-cell factor 1 and lymphoid enhancer factor 1 in clear cell renal cell carcinoma. Pathology Oncology Research, 19. (3), 545-551. doi: 10.1007/s12253-013-9615-3

Nikuševa Martić, Tamara, et al. "Expression of secreted frizzled-related protein 1 and 3, T-cell factor 1 and lymphoid enhancer factor 1 in clear cell renal cell carcinoma." Pathology Oncology Research, vol. 19, br. 3, 2013, str. 545-551. https://doi.org/10.1007/s12253-013-9615-3

Nikuševa Martić, Tamara, Ljiljana Šerman, Martina Zeljko, Željko Vidas, Slavko Gašparov, Hrvojka Marija Zeljko, Marin Kosović i Nives Pećina Šlaus. "Expression of secreted frizzled-related protein 1 and 3, T-cell factor 1 and lymphoid enhancer factor 1 in clear cell renal cell carcinoma." Pathology Oncology Research 19, br. 3 (2013): 545-551. https://doi.org/10.1007/s12253-013-9615-3

Nikuševa Martić, T., et al. (2013) 'Expression of secreted frizzled-related protein 1 and 3, T-cell factor 1 and lymphoid enhancer factor 1 in clear cell renal cell carcinoma', Pathology Oncology Research, 19(3), str. 545-551. doi: 10.1007/s12253-013-9615-3

Nikuševa Martić T, Šerman Lj, Zeljko M, Vidas Ž, Gašparov S, Zeljko HM, i sur.. Expression of secreted frizzled-related protein 1 and 3, T-cell factor 1 and lymphoid enhancer factor 1 in clear cell renal cell carcinoma. Pathology Oncology Research [Internet]. 07.2013. [pristupljeno 28.04.2024.];19(3):545-551. doi: 10.1007/s12253-013-9615-3

T. Nikuševa Martić, et al., "Expression of secreted frizzled-related protein 1 and 3, T-cell factor 1 and lymphoid enhancer factor 1 in clear cell renal cell carcinoma", Pathology Oncology Research, vol. 19, br. 3, str. 545-551, Srpanj 2013. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:191382. [Citirano: 28.04.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:191382
Podaci o radu
Naslov (engleski)Expression of secreted frizzled-related protein 1 and 3, T-cell factor 1 and lymphoid enhancer factor 1 in clear cell renal cell carcinoma
AutorTamara Nikuševa-Martić
AutorLjiljana Šerman
AutorMartina Zeljko
AutorŽeljko Vidas
AutorSlavko Gašparov
AutorHrvojka Marija Zeljko
AutorMarin Kosović
AutorNives Pećina-Šlaus
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Frequency and mortality of renal cell carcinoma (RCC) are increasing for decades. However, the molecular background of RCC tumorigenesis is still poorly understood. In current study we investigated the expression of TCF/LEF and SFRP family members (SFRP1 and SFRP3) to gain a better understanding of biological signaling pathways responsible for epidemiology and clinical parameters of clear cell RCC (cRCC). Thirty-six pairs of paraffin-embedded clear cRCC and adjacent nontumoral tissues samples using immunohistochemistry (IHC) were analyzed and compared with corresponding clinicopathological parameters. Immunohistochemistry indicated statistically significant decreased SFRP3 expression in tumor tissues but no consistency in SFRP1 expression in analyzed normal and tumor tissue. The TCF1 expression level was significantly weaker in normal tissue compared to tumor samples while LEF1 protein levels were significantly weaker in tumor tissue. To our knowledge, this is the first report on analysis of the expression of transcription factors TCF1 and LEF1 in clear cell renal cell carcinoma and their comparison with Wnt signal pathway antagonists belonging to SFRP family.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaPathology Oncology Research
Brojčani podacivol. 19, br. 3, str. 545-551
p-ISSN1219-4956
DOIhttps://doi.org/10.1007/s12253-013-9615-3
URN:NBNurn:nbn:hr:105:191382
Datum objave publikacije2013-07
URL dokumentahttps://doi.org/10.1007/s12253-013-9615-3
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-27 20:13:31