prikaz prve stranice dokumenta Prognostic factors in head and neck mucoepidermoid carcinoma: experience at a single institution based on 64 consecutive patients over a 28-year period
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Prognostic factors in head and neck mucoepidermoid carcinoma: experience at a single institution based on 64 consecutive patients over a 28-year period
International Journal of Oral and Maxillofacial Surgery, 47 (2018), 3; 283-288. https://doi.org/10.1016/j.ijom.2017.09.005
Granić, Marko; Suton, Petar; Mueller, Danko; Čvrljević, Igor; Lukšić, Ivica

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Citirajte ovaj rad

Granić, M., Suton, P., Mueller, D., Čvrljević, I. i Lukšić, I. (2018). Prognostic factors in head and neck mucoepidermoid carcinoma: experience at a single institution based on 64 consecutive patients over a 28-year period. International Journal of Oral and Maxillofacial Surgery, 47. (3), 283-288. doi: 10.1016/j.ijom.2017.09.005

Granić, Marko, et al. "Prognostic factors in head and neck mucoepidermoid carcinoma: experience at a single institution based on 64 consecutive patients over a 28-year period." International Journal of Oral and Maxillofacial Surgery, vol. 47, br. 3, 2018, str. 283-288. https://doi.org/10.1016/j.ijom.2017.09.005

Granić, Marko, Petar Suton, Danko Mueller, Igor Čvrljević i Ivica Lukšić. "Prognostic factors in head and neck mucoepidermoid carcinoma: experience at a single institution based on 64 consecutive patients over a 28-year period." International Journal of Oral and Maxillofacial Surgery 47, br. 3 (2018): 283-288. https://doi.org/10.1016/j.ijom.2017.09.005

Granić, M., et al. (2018) 'Prognostic factors in head and neck mucoepidermoid carcinoma: experience at a single institution based on 64 consecutive patients over a 28-year period', International Journal of Oral and Maxillofacial Surgery, 47(3), str. 283-288. doi: 10.1016/j.ijom.2017.09.005

Granić M, Suton P, Mueller D, Čvrljević I, Lukšić I. Prognostic factors in head and neck mucoepidermoid carcinoma: experience at a single institution based on 64 consecutive patients over a 28-year period. International Journal of Oral and Maxillofacial Surgery [Internet]. 03.2018. [pristupljeno 13.05.2024.];47(3):283-288. doi: 10.1016/j.ijom.2017.09.005

M. Granić, P. Suton, D. Mueller, I. Čvrljević i I. Lukšić, "Prognostic factors in head and neck mucoepidermoid carcinoma: experience at a single institution based on 64 consecutive patients over a 28-year period", International Journal of Oral and Maxillofacial Surgery, vol. 47, br. 3, str. 283-288, Ožujak 2018. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:871066. [Citirano: 13.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:871066
Podaci o radu
Naslov (engleski)Prognostic factors in head and neck mucoepidermoid carcinoma: experience at a single institution based on 64 consecutive patients over a 28-year period
AutorMarko Granić
AutorPetar Suton
AutorDanko Mueller
AutorIgor Čvrljević
AutorIvica Lukšić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Mucoepidermoid carcinoma (MEC) is the most common malignancy of the salivary glands. The clinical behaviour of MEC is largely unpredictable, ranging from indolent tumour growth to highly aggressive metastatic spread. The objective of this study was to determine the clinicopathological predictors of recurrence and survival in patients with head and neck MEC. The medical records of 64 patients who underwent surgical treatment for head and neck MEC between 1982 and 2010 were reviewed. The main outcome measures were disease-free survival (DFS) and overall survival (OS). Clinicopathological parameters evaluated were age, sex, anatomical subsite, histological grade, tumour stage, tumour size, adjuvant therapy, and nodal and margin status. For the entire cohort, the 5-year DFS was 82.8% and the 5-year OS was 67.2%. Histological grade and tumour subsite were statistically significant predictors of OS. Furthermore, tumour stage and nodal status were statistically significant predictors with respect to OS. Advanced tumour stage, high histological grade, submandibular/sublingual localization, and positive nodal status were independent predictors of the prognosis in patients with head and neck MEC. Further studies into the molecular biology of MEC are needed in order to provide new therapeutic strategies for patients with locally aggressive and highly metastatic carcinomas.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaInternational Journal of Oral and Maxillofacial Surgery
Brojčani podacivol. 47, br. 3, str. 283-288
p-ISSN0901-5027
DOIhttps://doi.org/10.1016/j.ijom.2017.09.005
URN:NBNurn:nbn:hr:105:871066
Datum objave publikacije2018-03
URL dokumentahttps://doi.org/10.1016/j.ijom.2017.09.005
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-28 09:15:31