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HDL subclasses and mortality in acute heart failure patients
Clinica Chimica Acta, 490 (2019); 81-87. https://doi.org/10.1016/j.cca.2018.12.020
Degoricija, Vesna; Potočnjak, Ines; Gastrager, Michaela; Pregartner, Gudrun; Berghold, Andrea; Scharnagl, Hubert; Stojaković, Tatjana; Tiran, Beate; Marsche, Gunther; Frank, Saša

Institucijski repozitorij: Dr Med - digitalni repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

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Degoricija, V., Potočnjak, I., Gastrager, M., Pregartner, G., Berghold, A., Scharnagl, H. ... Frank, S. (2019). HDL subclasses and mortality in acute heart failure patients. Clinica Chimica Acta, 490., 81-87. doi: 10.1016/j.cca.2018.12.020

Degoricija, Vesna, et al. "HDL subclasses and mortality in acute heart failure patients." Clinica Chimica Acta, vol. 490, 2019, str. 81-87. https://doi.org/10.1016/j.cca.2018.12.020

Degoricija, Vesna, Ines Potočnjak, Michaela Gastrager, Gudrun Pregartner, Andrea Berghold, Hubert Scharnagl, Tatjana Stojaković, Beate Tiran, Gunther Marsche i Saša Frank. "HDL subclasses and mortality in acute heart failure patients." Clinica Chimica Acta 490 (2019): 81-87. https://doi.org/10.1016/j.cca.2018.12.020

Degoricija, V., et al. (2019) 'HDL subclasses and mortality in acute heart failure patients', Clinica Chimica Acta, 490, str. 81-87. doi: 10.1016/j.cca.2018.12.020

Degoricija V, Potočnjak I, Gastrager M, Pregartner G, Berghold A, Scharnagl H, i sur.. HDL subclasses and mortality in acute heart failure patients. Clinica Chimica Acta [Internet]. 03.2019. [pristupljeno 24.12.2024.];490:81-87. doi: 10.1016/j.cca.2018.12.020

V. Degoricija, et al., "HDL subclasses and mortality in acute heart failure patients", Clinica Chimica Acta, vol. 490, str. 81-87, Ožujak 2019. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:930004. [Citirano: 24.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:930004
Podaci o radu
Naslov (engleski)HDL subclasses and mortality in acute heart failure patients
AutorVesna Degoricija
AutorInes Potočnjak
AutorMichaela Gastrager
AutorGudrun Pregartner
AutorAndrea Berghold
AutorHubert Scharnagl
AutorTatjana Stojaković
AutorBeate Tiran
AutorGunther Marsche
AutorSaša Frank
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
The link between HDL subclasses and the prognosis of cardiovascular diseases remains controversial. We thus evaluated the prognostic value of the HDL subclasses 3 and 2 cholesterol (HDL3-C, HDL2-C) as well as of total HDL-C for 3-month mortality in acute heart failure (AHF) patients. The serum levels of HDL3-C and total HDL-C were determined by detergent-based homogeneous assay. HDL2-C was computed by the difference between total HDL-C and HDL3-C. Out of the 132 analyzed patients, 35 (26.5%) died within three months after onset of AHF. Univariate logistic regression analyses revealed a significant inverse association of HDL3-C (odds ratio (OR) 0.46 per 1-SD increase, 95% confidence interval (CI) 0.27-0.72, p = 0.001) with 3-month mortality, whereas concentrations of total HDL-C and HDL2-C showed no significant association. After adjustment for various laboratory and clinical parameters known to be associated with mortality in heart failure patients, HDL3-C concentrations remained significantly associated with 3-month mortality (OR 0.34 per 1-SD increase, 95% CI 0.15-0.74, p =0.010). We conclude that low admission serum levels of HDL3-C are associated with an increased 3-month mortality in AHF patients, whereas total HDL-C and HDL2-C showed no association. HDL3-C might thus be useful as a prognostic parameter in AHF.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaClinica Chimica Acta
Brojčani podacivol. 490, str. 81-87
p-ISSN0009-8981
DOIhttps://doi.org/10.1016/j.cca.2018.12.020
URN:NBNurn:nbn:hr:105:930004
Datum objave publikacije2019-03
URL dokumentahttps://doi.org/10.1016/j.cca.2018.12.020
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-28 10:07:03