The breast is a paired organ composed of glandular and adipose tissue. In younger women, glandular tissue predominates, whereas, with aging, the breast undergoes involution, resulting in a significant increase in the proportion of adipose tissue. The majority of breast lesions are benign, with cysts and fibroadenomas being the most common. Carcinomas are less frequent than benign changes, but rank first in incidence and mortality among all malignant diseases in women. The implementation of a national breast cancer early detection program through mammographic screening has reduced mortality by approximately 20%. Radiological diagnosis of breast tumors encompasses mammography, ultrasound, and breast magnetic resonance imaging. Various procedures are performed under the guidance of these imaging methods, including fine-needle aspiration, core needle biopsy, and vacuum-assisted breast biopsy, which facilitate the determination of the nature of breast changes. Breast magnetic resonance imaging with contrast enhancement is the most sensitive radiological method for detecting breast pathology. However, the specificity of this method is limited, and the imaging process is time-consuming, more complex, and less accessible compared to mammographic and ultrasound examinations. Breast biopsy under magnetic resonance imaging guidance is indicated for lesions that are occult on mammography and ultrasound. This procedure is performed using a closed magnet and coils specifically designed for the breasts. Vacuum-assisted biopsy is most commonly performed due to its lower error rate and more precise diagnosis. Contraindications for the procedure include all contraindications for magnetic resonance imaging, as well as allergies to gadolinium or local anesthetics. Potentialcomplications of the procedure include hematoma formation, infection, and skin injury. This method is extremely precise, minimally invasive, and does not expose the patient to ionizing radiation. Conversely, the procedure is time-consuming, expensive, less accessible and requires highly trained personnel and specific equipment.