Radiological imaging methods play a key role in diagnosing and monitoring breast changes. The guidelines for diagnosing and monitoring breast lesions emphasize the importance of combining different radiological methods to achieve the highest possible accuracy of diagnosis and effectiveness of monitoring. Radiological methods such as mammography, ultrasound and magnetic resonance imaging are key in distinguishing between benign and malignant lesions. Mammography is the basic method for screening asymptomatic women due to its high sensitivity to detect microcalcifications. At the same time, ultrasound provides additional information in women with dense breasts and is useful in conducting biopsies. Magnetic resonance imaging offers high sensitivity for lesion detection with enhanced vascularization, while sonoelastography and digital tomosynthesis are new technologies that improve diagnostic accuracy. The paper also considers recommendations and guidelines for the application of these methods in various clinical situations, including screening in low and high-risk women, diagnosis of symptomatic patients, and monitoring after breast cancer treatment. The guidelines are essential to standardize access, improve the quality of care and ensure consistent results in diagnosing and treating breast disease. Regular updating of the guidelines in line with the latest scientific knowledge and technological advances is of crucial importance for ensuring optimal care for female patients. This paper provides a comprehensive overview of current guidelines and recommendations and highlights the importance of continuing education and adapting practice to the latest developments in radiological breast diagnosis.