Frozen embryo transfer (FET) is an increasingly common method of medically assisted reproduction in which a previously cryopreserved embryo is transferred to the uterus to treat infertility. Preparing the endometrium is necessary for each frozen embryo transfer and achieving its implantation. The success of this method largely depends on the receptivity of the endometrium and the synchronization of the endometrial receptivity with the developmental stage at which the embryo was cryopreserved. Today, there are several methods for preparing the endometrium: the natural cycle, the modified natural cycle with hCG administration, the HRT (artificial) cycle and the stimulated cycle. The natural and modified natural cycles are carried out in women with regular menstrual cycles, with the embryo transfer taking place in alignment with their cycles. The HRT cycle uses exogenous hormone supplementation of estrogen and progesterone to simulate a physiological cycle. Unlike the natural and stimulated cycles, a disadvantage of this method is the absence of corpus luteum formation, which is necessary for adaptation to cardiovascular changes during early pregnancy. As a result, an increased incidence of hypertensive disorders and pregnancy complications such as preeclampsia and macrosomia has been observed. The stimulated cycle is the method of choice for anovulatory women, and ovulation is most often induced using clomiphene citrate, letrozole, or low doses of FSH. According to current studies, no particular method has proven to be more effective than others regarding embryo implantation success and pregnancy outcomes. However, an individualized approach to endometrial preparation allows for therapy to be personalized to the specific needs of each patient, considering their unique characteristics and risk factors. This increases the chances of a successful pregnancy outcome, still additional research is essential to identify the best protocols and strategies in this process.