Objectives: To examine the association of different types of glycans with demographic parameters (age, sex, duration of disease), the amount of dopaminergic therapy and the severity of motor and non-motor symptoms in patients with Parkinson's disease Study design: cross-sectional study Participants and methods: The research was conducted on 30 patients suffering from idiopathic Parkinson's disease who are treated and monitored in the Clinic for Movement Disorders and the Day Hospital of the Neurology clinic of Clinical Hospital Centre in Osijek. The NMSS questionnaire was used to assess the severity of non-motor symptoms, and the MDS-UPDRS III scale was used to assess the severity of motor symptoms. For the purpose of the research, a questionnaire was constructed to record the demographic data of the patients. Results: A positive correlation of G0 glycans and glycan age, and a negative correlation of G2 glycans was observed with the duration of Parkinson's disease. A negative correlation of G2 glycans and the amount of dopaminergic therapy was found. No association of G0 and GS glycans with dopaminergic therapy was found, nor was there an association of G0, G2 and GS glycans with age, body mass index, and the severity of motor and non-motor symptoms. Conclusion: A negative correlation was found between G2 glycans and the duration of Parkinson’s disease, and a positive correlation of G0 glycans and glycan age was found with the duration of Parkinson’s disease. A negative correlation was observed between G2 glycans and the amount of dopaminergic therapy. No association was found between different types of glycans and the severity of motor and non-motor symptoms in patients with Parkinson's disease.