The use of non-prescription drugs among nursing students Objectives. The objective of the study was to examine the frequency of use of non-prescription drugs among nursing students and to determine whether there are differences between first and third year students. Study design. Cross-sectional study on two groups of subjects. Participants and methods. The study included 99 first and third year undergraduate nursing students at the Faculty of Medicine Osijek. It was conducted in April 2016. The method of research was an anonymous questionnaire designed for this purpose. It consists of 14 questions, to which the respondents gave answers related to their use of, and opinions on, OTC drugs. Results. Most of the first and third year respondents assessed their health as very good, and the majority of respondents from both years had either used OTC medicines once or twice in the past two months, or not even once. The most common causes among the respondents for the use of OTC medicines were pain, cold and cough, and fever, while problems with digestion and injuries were rare. According to these results, the most commonly used types of OTC drugs are analgesics and antipyretics. Conclusion. Results show that more than a half of first and third year respondents didn’t use OTC drugs even once or only used them once in the last two months. The most commonly used types of drugs are analgesics and antipyretics. Results indicate that respondents read the usage instructions about dosage and frequency of use of OTC drugs, and are familiar with their side effects.