Objectives: To survey the opinions of community nurses on the usefulness, organization, and implementation of national programs for early cancer detection; the role and motivation of a community nursing service in implementation and promotion of such programs; to identify potential differences of opinion between community nurses of variable work experiences and work places. Surveyed and methods: The survey included one hundred community nurses employed at public health centres in Vukovar, Vinkovci, Županja, Osijek, Đakovo, Slavonski Brod, and Beli Manastir. The survey was carried out through an anonymous questionnaire consisting of 43 questions, and was based on a questionnaire issued by the Croatian National Institute of Public Health. Results: Top scores, i.e. the highest correlation, were found amongst statements on usefulness, and least scores in statements on the organization and implementation of the National program for early cancer detection. There is no significant variance in grading the specific components of the National program for early cancer detection based on work experience length (p=0,806). Significantly higher grades for organization and implementation (Mann Whitney U test, p = 0,010), as well as awareness and education (Mann Whitney U Test < 0,001) of the National program for early cancel detection, were given by community nurses working in less populated areas (up to 50,000 citizens). The usefulness, role and motivation of community nursing service provides no significant variances in scores, while the overall score is significantly lower amongst community nurses working in more populated areas (over 50,000 citizens) (Mann Whitney U test, p = 0,038). Conclusion: Community nurses working in less populated areas have a better opinion of the usefulness, organization and implementation of the National program for early cancer detection, as well as the awareness and education of the public.