Study goal: The goals of the research are the monitoring of the quality of life of patients who have had a stroke with respect to the specific domain of living activities. Study drafting: A retrospective study was carried out at the clinic of internal diseases, KBC Osijek. Methods and participans: The survey included 72 respondents on the regular control after the stroke. The data was obtained by an anonymous survey of the patients that responded to the first control after the stroke. The control group consists of patients that were under medical treatment in the Clinic, from the other neurological conditions, but they never manifested symptoms that could connect them with a stroke. Results: There was a statistically significant difference between the quality of life of subjects with regard to the studied period (P = 0.003) and statistically significant difference with respect to the control group subjects (P = 0.001). No observed significant differences in individual domains of quality of life between the male and female sex after stroke has been found. The analysis of the data obtained in the study and conducted by comparing the coefficients of correlation connection was found to be the domain of the physical functioning in patients after treatment of the CVI– and significantly larger than the same domain connections at the control group (P = 0.046). Conclusion: The analysis of the data obtained to the behavior in all the available research, and in the research conducted at the clinic for cerebrovascular disease confirmed a significant impact of the stroke on the quality of life of the person concerned. From the standpoint of the health functioning form, there are evident disorders in every form of health functioning.