Research Aim. The aim of the research was to study the quality of life level of full-time and part-time nursing students and whether there is a difference in the quality of life. Specific objectives were the following: •to asses if there is a difference in students' quality of life with respect to age, •to asses if there is a difference in students' quality of life with respect to sex, • to asses if there is a difference in students' quality of life with respect to employment status. Research Draft. A cross-sectional survey was conducted at the Faculty of Medicine in Osijek among undergraduate and graduate nursing students. Subjects and Methods. The subjects were first, second and third year nursing students of the undergraduate university studies and first and second year nursing students of the graduate university studies at the Faculty of Medicine in Osijek. There were 223 subjects in this research and it was conducted during April and May 2017. An anonymous self-assessment questionnaire was used as the research instrument - THE WORLD HEALTH ORGANIZATION QUALITY OF LIFE (WHOQOL - BREF). Results. From the perspective of factors Life and personal appearance satisfaction and Life needs satisfaction and relationships with others there is no significant statistical difference among the subjects replies with respect to sex, age, year of study, marital and employment status or age. Conclusion. The quality of life in full-time and part-time nursing students was rated as “quite good“ by the subjects', and there is no statistically significant difference in the quality of life of full-time and part-time nursing students.