Research aim: to gather data about smoking tobacco, drinking alcohol and psychoactive drugs usage among medical students at Faculty of Medicine in Osijek and to analyze students' socioeconomic status, who they live with while studying, whether they receive scholarship or any other type of help, in what types of societies they are members of, whether they often change sexual partners and whether they use protection. Study structure: cross-sectional study Subjects: The research was conducted at Faculty of Medicine in Osijek among first-, second-, third-, fifth- and sixth-year students of all study programs. Subjects are informed about the research and they consciously and willingly signed consent form for participating in the research. Results: Data processing from 111 subjects is finished. Subject are between 19 and 41 years old. The majority of students lives in a family home with their parents, whereas a small number of students lives in a dorm. It has been determined that students in equal measure use addictive drugs, play games of chance, use protection and spend their quality time with friends and family. Conclusion: Subjects of all study programs expressed their opinion that a half or more than a half of the students smoke, students of all years of study equally think that it takes one or several hours for drug acquisition. Students of all years of study consume alcohol, more than 85 % of subjects have never experienced any alcohol-related consequences. Among subjects playing games of chance, the majority plays lottery. Subjects of all years of study have had one sexual partner and use a condom as protection. Subjects of all years of study spend their free time hanging out with friends or their sexual partner. The favorite place for subjects of all years of study is a private place, such as at a friend's house.