Naslov Depresivnost u oboljelih od medularnog karcinoma štitnjače Naslov (engleski) Depression in patients with medullary thyroid carcinoma Autor Ivana Kristina Delić Mentor Maja Radman (mentor)Ustanova koja je dodijelila Sveučilište u Splitu Datum i država obrane 2014, Hrvatska Znanstveno / umjetničko BIOMEDICINA I ZDRAVSTVO Sažetak CILJ ISTRAŽIVANJA:
Cilj ovog istraživanja je bio utvrditi postojanje i povezanost depresivnosti s
medularnim karcinomom štitnjače.
ISPITANICI I METODE:
Istraživanje je provedeno na Klinici za nuklearnu medicinu i Klinici za
endokrinologiju KBC-a Split. Uključivalo je one bolesnike koji su bili hospitalizirani pod
dijagnozom medularnog karcinoma štitnjače u razdoblju od 14 godina (2000. - 2014.). Podatci
su retrospektivno prikupljeni iz kartoteke povijesti, među ispitanicima je usmeno proveden
upitnik Beckov inventar depresije, te je sve obrađeno u programu Microsoft Office Excel
2007.
REZULTATI:
U razdoblju od 14 godina (2000. - 2014.) analizirano je 38 od 41 bolesnika, a od toga 26
žena i 12 muškaraca. Među bolesnicima je bilo 13 onih kojima je bolest otkrivena u dobi
između 40 i 50 godina, 11 kojima je bolest otkrivena u dobi između 50 i 60 godina, 7 kojima
je bolest otkrivena u dobi između 60 i 70 godina, te 3 bolesnika kojima je bolest otkrivena u
dobi manje od 40 godina. Veći broj bolesnika je bio iz prigradskih područja (n=21) nego iz
grada (n=17). Prema obrazovanju veći broj bolesnika je imalo stupanj srednje stručne spreme
(n=24) nego stupanj visoke stručne spreme (n=14). Analizom je utvrđeno da je 10 muških
bolesnika, te 22 bolesnice imalo povišene vrijednosti kalcitonina preoperativno. Nakon
operativnog zahvata 24 od ukupnog broja bolesnika je imalo povišene vrijednosti kalcitonina
postoperativno. Nakon provedenog upitnika Beckov inventar depresije utvrđeno je da je
najveći broj bolesnika minimalno depresivan (n=22), zatim slijede umjereno depresivni (n=6),
teže depresivni (n=6) i blago depresivni (n=4). Postoji statistički značajna razlika u
odgovorima na upitnik s obzirom na dob otkrivanja bolesti (p=0,0001), te razlika među
odgovorima onih kojima je bolest dijagnosticirana prije i onih kojima je bolest
dijagnosticirana poslije 51. godine života (p=0,0066).
ZAKLJUČAK:
Medularni karcinom štitnjače se češće pojavljuje kod žena, i to u dobi između 40 i 50
godina. Ovim istraživanjem nije dokazana povezanost depresivnosti i medularnog karcinoma
štitnjače, jer je najveći broj bolesnika minimalno depresivan.
Sažetak (engleski) OBJECTIVES:
The aim of this study was to determine the association of depression with medullary
carcinoma of the thyroid.
EXAMINEES AND METHODS:
The study was conducted at the Department of nuclear medicine and Department of
endocrinology, University hospital Split. It included all patients who were hospitalized under
the diagnosis of medullary thyroid carcinoma in a period of 14 years (2000 - 2014). Data were
retrospectively collected from the medical history files, Beck depression inventory was
verbally conducted among respondents, and all that was processed in Microsoft Office Excel
2007.
RESULTS:
In a period of 14 years (2000 - 2014) 38 of 41 patients were analyzed, of which 26 women and
12 men. Among them, there were 13 of those to whom the disease was detected between the
ages of 40 and 50, 11 where the disease was detected between the ages of 50 and 60 years, 7
where the disease was detected between the ages of 60 and 70 years, and 3 patients whose
disease discovered at the age less than 40 years. A larger number of patients was from
suburban areas (n = 21) than the city (n = 17). By education a higher number of patients had
secondary level of education (n = 24) than the level of a university degree (n = 14). The
analysis found that 10 of the respondents male and 22 female patients had elevated calcitonin
preoperatively. After surgery, 24 of the total number of patients had elevated calcitonin
postoperatively. After completing the questionnaire Beck Depression Inventory was found
that the largest number of minimally depressed patients (n = 22), followed by moderately
depressed (n = 6), the harder depressed (n = 6) and slightly depressed (n = 4). There was a
statistically significant difference in the responses to the questionnaire with respect to age
detection of disease (p = 0.0001), and the difference between the responses of those whose
disease was diagnosed before and those who have been diagnosed with the disease after 51
years of age (p = 0.0066).
CONCLUSION:
Medullary thyroid cancer occurs more often in women, and between the ages of 40 and 50
years. This research has not been proven correlation depression and medullary thyroid cancer,
since the majority of patients minimally depressed.
Ključne riječi
Novotvorine štitnjače
Medularni karcinom
Depresija
Ključne riječi (engleski)
Thyroid Neoplasms
Carcinoma Medullary
Depression
Jezik hrvatski URN:NBN urn:nbn:hr:171:112243 Studijski program Naziv: Medicina Vrsta resursa Tekst Način izrade datoteke Izvorno digitalna Prava pristupa Pristup korisnicima matične ustanove Uvjeti korištenja Datum i vrijeme pohrane 2016-03-15 07:23:15
