Objectives: The aim of this study was to examine physical activity in individuals with PTSD. An additional objective was to compare sociodemographic characteristics, anthropometric features, habits, laboratory parameters and symptoms of depression, anxiety and insomnia in individuals with PTSD who are more physically active compared to those who are less physically active. Patients and methods: The study included 66 male war veterans diagnosed with PTSD. During regular examinations at the Center for Psychotrauma, anamnestic data regarding gender, age, socioeconomic status, level of education, and habits were collected. Anthropometric measurements and body composition assessments were conducted as part of the study. The participants' physical activity was assessed using the International Physical Activity Questionnaire. Venous blood samples were taken from the patients, and laboratory parameter values were obtained. Results: Out of a total of 66 participants diagnosed with PTSD, 27 (40.9%) were inactive or minimally active. Patients who were more physically active had a lower body mass index (P=0.049). Less physically active patients were also less likely to consume alcohol compared to more physically active patients (P=0.014). Participants who were more physically active had lower HbA1c values than those who were less active. Among the more active population, there was no statistically significant difference in the prevalence of smokers compared to less active individuals (P=1). Less physically active patients did not differ in the presence of insomnia (P = 0.273), anxiety (P = 0.463), and depressive mood (P = 0.624) compared to more physically active patients. There was no association between socioeconomic status and level of education, as well as lipid levels, with patients' physical activity (P = 0.222 and P = 0.497). Conclusion: In individuals with PTSD, a high prevalence of sedentary or minimally active individuals has been confirmed. PTSD patients who were more physically active had significantly lower BMI values, significantly higher alcohol consumption, and lower HbA1c values compared to less physically active PTSD patients. Physical activity in individuals with PTSD did not affect symptoms of depression, anxiety, and insomnia. Individuals who were more physically active did not differ from less physically active individuals in lipid levels, percentage of body fat, and estimated metabolic age.