Research objectives: The aim of this study to investigate connection of the motivation, hope and decisional conflict on lymphatic drainage efficacy in women after breast cancer operation considering level of education and age. Methods: The study has been conducted based on the one-time interviewing and measuring volume of the arm in the beginning and in the end of the physical therapy in women after breast cancer operation. The study has been conducted on the tertiary levels of the Department of physical medicine and rehabilitation with rheumatology , Clinical Hospital Center Split during the period from May to September 2016. This study included 75 subjects that went through the manual lymphatic drainage as a physical therapy method. The source of the information was a form for measuring volume of upper extremity and questionnaires: questionnaire on personal data, motivation test, hope test and decisional conflict test. Results: The results of this study have shown that there was no statistically significant relation between manual lymphatic drainage efficacy and level of education, and also there was no statistically significant relation between manual lymphatic drainage efficacy and age. It has been found that there was no statistically significant relation between manual lymphatic drainage efficacy and motivation, distributing motivation on intrinsic and extrinsic it has been found statistically significant positive correlation between manual lymphatic drainage efficacy on 50 cm point of measure from distal part of the middle finger and intrinsic motivation. There was no statistically significant relation between manual lymphatic drainage efficacy and extrinsic motivation. It has been found that there was statistically significant positive correlation between manual lymphatic drainage efficacy on 50 cm point of measure from distal part of the middle finger and hope. This study has also shown that there was statistically significant negative correlation between manual lymphatic drainage efficacy on 10 cm point of measure from distal part of the middle finger and decisional conflict. Conclusion: This study has shown that a psychological factors i.e. motivation, hope and decisional conflict and demographic factors i.e. level of education and age do not influence on lymphatic drainage efficacy in women after breast cancer operation.