Dual-Energy CT is the new method that helps us to observe human body. DECT provides information about how substances behave at different energies (80 kVp i 140 kVp) and it can be used to provide quantitative information about tissue composition. Material density images may help improve lesion characterization while minimizing the radiation. Datasets obtained with DECT can be used to reconstruct virtual unenhanced images which results in radioation dose reduction. Also, it requires less acquisition time. Recent technology improvements have facilitated the maturation of DECT into a reliable clinical tool. In the abdomen and pelvis, dual-energy CT may be used in the liver to increase conspicuity of hypervascular lesions; in the kidneys, to distinguish hyperattenuating cysts from enhancing renal masses and to characterize renal stone composition; in the adrenal glands, to characterize adrenal nodules; and in the pancreas, to differentiate between normal and abnormal parenchyma. Imaging at lower energies (80 kVp) optimizes conspicuity of hypervascular lesions in solid organs, and iodine maps can be superimposed on morphologic imaging to show contrast enhancement. Advanced postprocessing DECT applications include the discrimination of various renal stone types and the quantification of hepatic iron deposition, even if complicated by the presence of hepatic steatosis. Although DECT has been proven to be a reliable technique that is supported by a broad spectrum of articles, caution must be exerted because minor artifacts and limited coverage of the abdominal circumference, depending on the DECT technology used, may be observed, especially in obese patients. This could potentially compromise image interpretation in a minority of cases.