This retrospective study investigated the incidence of certain congenital brain anomalies in children with disorders of neurological development. who were treated at the Clinical Department of Neurology and Endocrinology, Pediatric's Clinic, University Hospital Split. The study included 146 children of both sexes (82 boys and 64 girls) and of different ages. Neuroradiological evaluation included computed tomography scanning and magnetic resonance imaging. Neural developmental anomalies had the highest incidence in our study population.l. This type of anomaly of the central nervous system was diagnosed in 43/146 patients (29.45%). The second most common group of disorders belong to anomalies of ventral induction diagnosed in 35/146 (23.97%) patients. The third most common group anomalies in our population were disorders of cortical development, and disorders of neuronal migrationwhich were diagnosed in 27/146, or 18.49% of the patients. Disorders of proliferation of neurons were found in 24/146 patients (16.44%). The smallest group of brain anomalies belong to disorders of cortical organization (17/146 or 11.64%). Genetic testing of blood samples in10 patients (2 girls and 8 boys) confirmed variouschromosomopathies (fragile X syndrome chromosome. trisomy 8, trisomy of 22. chromosome); Di George syndrome and Prader-Willi syndrome. Lissencephaly was the most common brain anomaly identified by neuroimaging associated with chromosomopathies (together with agenesis of corpus callosum or as an isolated disorder). Significant and continuous development of modern neuroradiological techniques (especially magnetic resonance imaging) during the last decade has led to new insights and classification of developmental anomalies of the brain. This study, which includes a ten-year period in children who were treated for a variety of neurodevelopmental disorders is determined by a wide variety of anomalies. Representation of certain groups of anomalies was in accordance with previous similar studies and data from the literature. For all-inclusive thing understanding of brain malformation, a necessary multidisciplinary approach that includes experts from the fields of neurology neuropaediatrics, embryology, neuro-genetics and neurochemistry.