With this paper we wanted to explore the patient's perception of medications. It is a wrong assumption that the patient, prior to the contact with a health professional, has no views about therapy and medicine in general. Numerous studies, including ours, are determined that the patient's views and perceptions very often do not correspond with the actual effect of medication. The patient's views and perceptions of medications are often in collision with advice provided by a doctor, or a pharmacist. In order to determine the patient's perception of the medications, we used a questionnaire that contained 8 questions (in which are more claims) about the medicine, effectiveness and efficiency, the medicinal necessities or their concerns about the side effects and adherence to the prescribed therapy. 117 patients from Zagreb were questioned, who have pick up one or more medications at the pharmacy. Our research has shown that respondents have numerous inaccurate perceptions or misperceptions about the medications. Patients find that medication is only what the doctor prescribes. Medications that are not prescribed by a doctor, or a medicine that doesn't need a prescription (over-the-counter, dietary supplements and herbal supplements) are not considered as medicines in the strict sense of the word. It is a great delusion that is widespread among the population. The respondents further, wrong again, consider that there's only one effect and that is a positive, therapeutic effect. In other words, respondents considered that the medications have no additional side effects. Particularly concerning is the fact that the majority of patients, at the first signs of healing interrupt their therapy. From all the above we conclude that a pharmacist should be aware of patient's perception of the medication and give them instructions to use the medicinal (dose, dosing interval, combinations with other drugs or food) and adjust therapeutic effect to each patient individually and coordinate with his personal perception of the medication.