Fungi from the genera Aspergillus, Penicillium, and Talaromyces are among the most prevalent fungal contaminants found in damp-damaged living environment, posing significant health risks to inhabitants. These fungi can trigger various acute and chronic health issues. To assess the extent of contamination, indoor air samples were collected from an apartment with visible mould growth and outdoor air samples were collected as a control Among all the isolated fungi, those affiliated with the genera Aspergillus, Penicillium, and Talaromyces were specifically selected for further analysis. Identification was carried out at the species level utilizing partial calmodulin (CaM) gene sequencing, with obtained nucleotide sequences compared against the NCBI database. Among Aspergilli (13/35 isolates) A. jensenii was the most dominating species (9/13) while there was only one isolate each of A. creber, A. puulaauensis, A. aureolatus and A. welwitschiae. P. chrysogenum/rubens was the most frequent Penicillium species (8/24), two of which were from outdoor air samples. Other Penicillia included P. expansum (3/24), P. polonicum (2/24), P. speluncae (2/24), P. allii (1/24), P. commune (1/24) and P. digitatum (1/24). One of each isolates of P. biourgeianum, P. brevicompactum and P. kongii were only only identified among outdoor air isolates. The single isolate assigned to the Talaromyces sp. was identified as T. wortmannii. Although CaM provided more precise species identification compared to the the ITS molecular marker, it showed a limitation in distingishing P. commune from P. palitans and P. camemberti as well as P. chrysogenum and P. rubens. Based on the available literature, the identified species pose a significant health threat to occupants exposed to them, primarily due to their concerning array of secondary metabolites. This underscores a related long-term health risk associated with residing in damp and mouldy housing. Moreover, it highlights the necessity for additional research, given the prevalence of this issue.