The life cycle of plants i animals begins with the fertilization of the egg cell, which results in the formation of a zygote. Shortly after fertilization, the development of the embryo relies on transcripts inherited from the egg cell. Gradually, the zygote/embryo takes control of development during the maternal-to-zygotic transition (MZT). Maternal-to-zygotic transition occurs progressively through the degradation of inherited maternal transcripts and the activation of the zygotic genome (ZGA). Unlike animals, in plants zygotic genome activation begins at the zygote stage and it leads to the first cell division. Genes expressed during the early stages of plant development are involved in establishing the polarity of the zygote and the apical-basal axis, which is essential for further embryogenesis. The mechanisms which govern degradation of inherited transcripts in plants are still unknown. Previous studies suggest differences in the process of maternal-to-zygotic transition between monocots and dicots. Recent research on animal models has highlighted the importance of alternative splicing in the MZT process, but such studies are yet to be conducted on plant models. The MATH-BTB protein family presents perspective for studying alternative splicing in the context of MZT process in Arabidopsis.