There are extremely dangerous and poisonous marine organisms in the world, but they are generally residents of tropical sea. There is no reason to panic about residents of the Adriatic Sea. However, some species of phanerotoxic and cryptotoxic fish live there. Examples of phanerotoxic fish are Rajiformes, Scorpaeniformes and Trachinidae. These are fish that by their poisonous appliances and spikes directly inject poison into victims. While cryptotoxic species are morays, eels and congers. Their blood contains certain toxins that can be harmful if consumed rough fish. In addition to these inhabitants of Adriatic Sea, Sphoeroides pachygaster, which contains tetrodotoxin, the most powerful fish poison, established its population. Tetrodotoxin has exceptionally fast activity, and death occurs due to respiratory paralysis. Poisons of these species consist mainly of thermolabile protein toxins, which decompose bringing the heat and lose activity with a strong hypothermia. In our country people are often the victims of stab poisoning than consumption. In case of poisoning people should seek professional help because of problems arising from the action of poisons, and to repair the wounds due to mechanical tissue damage that could cause a secondary infection.