Endemic species are taxa that live on geographically restricted area. According to Nikolić, endemic flora of Croatia consists of 384 species and subspecies of which are 110 stenoendemic and 274 endemic species. Their value is primarily biological but also estetic. Their protection is very important and can be protected in two ways, by protection of area and protection of species. Endemic species can often be found in heavily reachable places that are under small anthropogenic influence. However, these kind of areas are nowadays less present so precisely planned ways of protection are needed. For example, 'ex situ' protection which reduces the devastation of natural populations by licensed cultivation and selling of endemic species. The Botanical Garden of the Faculty of Science in Zagreb has the permission of Ministry of Protection of Environment and Nature, precisely of State Directorate for Environmental Protection and State Institute for Protection of Nature for 'ex situ' programme. A few horticultural interesting endemic species are represented. Some of them are already in the programme and some aren't yet. Those are Chouardia litardierei, Degenia velebitica, Iris adriatica, Campanula fenestrellata ssp. istriaca, Petteria ramentacea, Helleborus niger ssp. macranthus, Dianthus giganteus ssp. croaticus and Alyssum montanum ssp. pluscanescens.