Steroid hormones are very important group of hormones; and all are a common outcome combination of cholesterol. The most important are aldosterone, cortisol, estrogen, progesterone and testosterone, which operate at almost all the important systems in the body and maintain homeostasis. They are specific becouse they occur in a particular gland, are excreted to the blood and are bound to plasma proteins transferred to target organs where they will operate. All steroid hormones are regulated by negative feedback system, which ensures that the hormone is always present in optimal quantities. To initiate action, they must enter the target cells. There they work on increasing protein synthesis, and their effect is not immediate but delayed for some time. Excretion disorders may be excessive or inadequate secretion of hormones. Excessive secretion is usually treated by removing the gland or irradiation of a gland affected by illness. Reduced secretion compensates entering pharmaceutically produced steroid hormones, in order to compensate for the lack of natural production. Useful effects of steroid hormones with speeding up metabolism and increasing muscle mass are used by training elite and amateur athletes to improve sports results. Today, the androgenic steroids in elite sports is strictly prohibited because it does not give the actual capabilities of individual athletes, causing numerous serious side effects that are not only detrimental to health, but can be life threatening if they are used for a long period of time.