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Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe
Physical Review Letters, 114 (2015), 7; 78103. https://doi.org/10.1103/PhysRevLett.114.078103
Glunčić, Matko; Maghelli, Nicola; Krull, Alexander; Krstić, Vladimir; Ramunno-Johnson, Damien; Pavin, Nenad; Tolić, Iva M.

Institucijski repozitorij: Repozitorij Prirodoslovno-matematičkog fakulteta

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Glunčić, M., Maghelli, N., Krull, A., Krstić, V., Ramunno Johnson, D., Pavin, N. i Tolić, I. M. (2015). Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe. Physical Review Letters, 114. (7). doi: 10.1103/PhysRevLett.114.078103

Glunčić, Matko, et al. "Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe." Physical Review Letters, vol. 114, br. 7, 2015. https://doi.org/10.1103/PhysRevLett.114.078103

Glunčić, Matko, Nicola Maghelli, Alexander Krull, Vladimir Krstić, Damien Ramunno Johnson, Nenad Pavin i Iva M. Tolić. "Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe." Physical Review Letters 114, br. 7 (2015). https://doi.org/10.1103/PhysRevLett.114.078103

Glunčić, M., et al. (2015) 'Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe', Physical Review Letters, 114(7). doi: 10.1103/PhysRevLett.114.078103

Glunčić M, Maghelli N, Krull A, Krstić V, Ramunno Johnson D, Pavin N, i sur.. Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe. Physical Review Letters [Internet]. 2015. [pristupljeno 24.12.2024.];114(7). doi: 10.1103/PhysRevLett.114.078103

M. Glunčić, et al., "Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe", Physical Review Letters, vol. 114, br. 7, 2015. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:217:788975. [Citirano: 24.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:217:788975
Podaci o radu
Naslov (engleski)Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe
AutorMatko Glunčić
AutorNicola Maghelli
AutorAlexander Krull
AutorVladimir Krstić
AutorDamien Ramunno-Johnson
AutorNenad Pavin
AutorIva M. Tolić
Autorova ustanovaSveučilište u Zagrebu
Prirodoslovno-matematički fakultet
(Fizički odsjek)
Znanstveno / umjetničko
područje, polje i grana		PRIRODNE ZNANOSTI
Fizika
Znanstveno / umjetničko
područje, polje i grana		PRIRODNE ZNANOSTI
Biologija
Sažetak (engleski)
In fission yeast, microtubules push against the cell edge, thereby positioning the nucleus in the cell center. Kinesin-8 motors regulate microtubule catastrophe; however, their role in nuclear positioning is not known. Here we develop a physical model that describes how kinesin-8 motors affect nuclear centering by promoting a microtubule catastrophe. Our model predicts the improved centering of the nucleus in the presence of motors, which we confirmed experimentally in living cells. The model also predicts a characteristic time for the recentering of a displaced nucleus, which is supported by our experiments where we displaced the nucleus using optical tweezers.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaPhysical Review Letters
Brojčani podacivol. 114, br. 7, 78103
p-ISSN0031-9007
e-ISSN1079-7114
DOIhttps://doi.org/10.1103/PhysRevLett.114.078103
URN:NBNurn:nbn:hr:217:788975
Datum objave publikacije2015
URL dokumentahttp://link.aps.org/doi/10.1103/PhysRevLett.114.078103
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Javna napomenaCopyright (2015) by the American Physical Society. (Received 5 May 2014; revised manuscript received 14 December 2014; published 18 February 2015.
Datum i vrijeme pohrane2020-01-11 12:58:10