During the Green Revolution semi-dwarf varieties of wheat and rice were introduced, which quickly became the basis of today's agriculture due to easier cultivation and higher yields. (Peng et al., 1999; Hedden, 2003). These varieties accumulate DELLA proteins that prevent the transcription of the gibberellin-dependent genes, thereby preventing plant growth. Green revolution varieties show reduced nitrogen use efficiency, which is why large amounts of nitrogen fertilizers have to be used in their cultivation. Excess nitrogen fertilizers can be harmful for the environment. The GRF4 protein is a transcriptional activator that stimulates the transcription of genes responsible for nitrogen assimilation and metabolism, but also affects carbon metabolism. Accumulation of DELLA proteins prevents positive regulation of genes mediated by the GRF4 protein (Li et al., 2018). One of the characteristics of the Green revolution varieties is also increased yield at higher concentrations of available nitrogen. The protein responsible for this response is the transcription factor NGR5 which stimulates nitrogen dependent H3K27me3 histone methylation mediated by the PRC2 complex. This methylation represses the genes responsible for inhibiting lateral branching. NGR5 is degraded in the presence of gibberellin via the GID1 receptor. Accumulation of DELLA proteins competitively inhibits this degradation, thereby stabilizing NGR5 and consequently stimulating tillering (Wu et al., 2020). Overexpression of GRF4 and NGR5 proteins can enhance nitrogen use efficiency and increase the yield of Green Revolution varieties even in low nitrogen conditions, without interfering with the semi-dwarf phenotype.